Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.59 |
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CFTR | P13569 | 1/20 | 0.52 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.52 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5506588 | 0.81 | ACHE (0.62) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4011575 | 0.76 | ACHE (0.60) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL13961400 | 0.76 | ACHE (0.60) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3909641 | 0.74 | ACHE (0.69) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5511124 | 0.74 | ACHE (0.69) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL3892901 | 0.74 | ACHE (1.00) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29638891 | 0.74 | ACHE (1.00) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL30168025 | 0.73 | ACHE (0.52) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL5506248 | 0.72 | ACHE (0.51) | ACHEBCHEALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28922104 | 0.71 | ACHE (0.47) | ACHEBCHEALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4472399-A | Indolo[2',3';3,4]pyrido[2,1-b]quinazoline-5-ones, a process for the preparation thereof, and diuretic compositions and methods using them | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1984-09-18 | — | — | US | disclosed |
| US-4395549-A | CHEMICAL INTERMEDIATES FOR RUTECARPINE DIURETICS | CHINOIN GYOGYSZER ES VEGYESZETI TERMEKEK GYARA RT. (HU) | 1983-07-26 | — | — | US | disclosed |