Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pimagedine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pimagedine SCHEMBL27784772 | 1.00 | TSHR (0.50) | — | |
| Pimagedine SCHEMBL6665719 | 1.00 | TSHR (0.50) | — | |
| Pimagedine SCHEMBL9952232 | 1.00 | TSHR (0.50) | — | |
| Pimagedine SCHEMBL28272894 | 0.97 | TSHR (0.47) | — | |
| Pimagedine SCHEMBL3279095 | 0.97 | LMNA (0.53) | — | |
| Oxalic Acid SCHEMBL507710 | 0.90 | TSHR (0.47) | — | |
| Oxalic Acid SCHEMBL507712 | 0.90 | TSHR (0.47) | — | |
| Pimagedine SCHEMBL1640210 | 0.89 | — | — | |
| Pimagedine SCHEMBL27920035 | 0.88 | CYP1A2 (0.40) | — | |
| Oxalic Acid SCHEMBL4946423 | 0.87 | TSHR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2974 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12533303-B2 | Composition for the simultaneous bleaching and dyeing of keratin fibres and process using this composition | L'OREAL (FR) | 2026-01-27 | — | — | US | claimed |
| US-20260007583-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2026-01-08 | — | — | US | claimed |
| US-20250387309-A1 | METHOD FOR THE TREATMENT OF KERATIN FIBRES COMPRISING A PRETREATMENT OR POST-TREATMENT STEP | OREAL (FR) | 2025-12-25 | — | — | US | claimed |
| US-20250381106-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-18 | — | — | US | claimed |
| US-20250381107-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-18 | — | — | US | claimed |
| US-20250375361-A1 | COMPOSITION FOR LIGHTENING KERATIN FIBRES AND PROCESS FOR LIGHTENING KERATIN FIBRES USING SAID COMPOSITION | OREAL (FR) | 2025-12-11 | — | — | US | claimed |
| US-20250375366-A1 | PROCESS FOR TREATING KERATIN FIBRES USING A CARNITINE SALT OR A CARNITINE DERIVATIVE | OREAL (FR) | 2025-12-11 | — | — | US | claimed |
| EP-4633791-A1 | PROTEIN-BASED MICROCAPSULES | Firmenich SA (CH) | 2025-10-22 | — | — | EP | claimed |
| US-20250281371-A1 | PLANT PROTEIN-BASED MICROCAPSULES | FIRMENICH SA (CH) | 2025-09-11 | — | — | US | claimed |
| US-12365853-B2 | Cleavable multi-alcohol-based microcapsules | FIRMENICH SA (CH) | 2025-07-22 | — | — | US | claimed |
| CN-86101786-A | Produce the printable composition of embossed decorative sheets | — | 1986-11-05 | — | — | CN | claimed |
| EP-0192218-A2 | Printable composition for making embossed decorative sheets | CONGOLEUM CORPORATION (US) | 1986-08-27 | — | — | EP | claimed |
| US-4565014-A | Process for drying aminoguanidine bicarbonate | OLIN CORPORATION (US) | 1986-01-21 | — | — | US | claimed |
| EP-0167251-A1 | Process for drying aminoguanidine bicarbonate | OLIN CORPORATION (US) | 1986-01-08 | — | — | EP | claimed |
| EP-0146219-A1 | Aminophosphonic & aminophosphinic acid derivatives processes for their preparation & herbicidal compositions containing them | Geshuri Laboratories Ltd. (IL) | 1985-06-26 | — | — | EP | claimed |
| US-4295982-A | PRODUCT FROM SULFUR, AMINOGUANIDINE, UNSATURATED ACID; CORROSION RESISTANCE | MOBIL OIL CORPORATION (US) | 1981-10-20 | — | — | US | claimed |
| US-4149980-A | AMINOGUANIDINE SULFONATE OVERBASED COMPOUND | STANDARD OIL COMPANY (INDIANA) (US) | 1979-04-17 | — | — | US | claimed |
| US-4045305-A | Cadmium electroplating bath and process | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1977-08-30 | — | — | US | claimed |
| US-3998707-A | Cadmium electroplating process and bath therefor | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1976-12-21 | — | — | US | claimed |
| US-3963842-A | Deposition of copper | LONDON LABORATORIES LIMITED CO. (US) | 1976-06-15 | — | — | US | claimed |