Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
| ▸ | LDHB | P07195 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL507710 | 1.00 | TSHR (0.47) | TSHRNFKB1CYP1A2MAOAMAOB | |
| Oxalic Acid SCHEMBL508423 | 0.97 | TSHR (0.44) | TSHRNFKB1CYP1A2MAOAMAOB | |
| Oxalic Acid SCHEMBL508424 | 0.97 | TSHR (0.44) | TSHRNFKB1CYP1A2MAOAMAOB | |
| Oxalic Acid SCHEMBL4946423 | 0.97 | TSHR (0.44) | TSHRNFKB1CYP1A2MAOAMAOB | |
| Pimagedine SCHEMBL40128 | 0.90 | — | — | |
| Pimagedine SCHEMBL27784772 | 0.90 | TSHR (0.50) | TSHRNFKB1CYP1A2MAOAMAOB | |
| Pimagedine SCHEMBL9952232 | 0.90 | TSHR (0.50) | TSHRNFKB1CYP1A2MAOAMAOB | |
| Pimagedine SCHEMBL6665719 | 0.90 | TSHR (0.50) | TSHRNFKB1CYP1A2MAOAMAOB | |
| Pimagedine SCHEMBL3279095 | 0.87 | LMNA (0.53) | TSHRNFKB1CYP1A2MAOAMAOB | |
| Pimagedine SCHEMBL28272894 | 0.87 | TSHR (0.47) | TSHRNFKB1CYP1A2MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119753848-A | Amino guanidine oxalate second-order nonlinear optical crystal material, preparation and application thereof | 同济大学 | 2025-04-04 | — | — | CN | claimed |
| CN-117836271-A | Salts of phenylpyrrolaminoguanidine and polymorphs of phenylpyrrolaminoguanidine onium salts | 西奈克制药有限公司 | 2024-04-05 | — | — | CN | claimed |
| US-8425702-B2 | Precursor of an explosive composition including at least one ionic liquid and a method of desensitizing an explosive composition | ALLIANT TECHSYSTEMS INC. (US) | 2013-04-23 | — | — | US | claimed |
| US-20120024437-A1 | PRECURSOR OF AN EXPLOSIVE COMPOSITION INCLUDING AT LEAST ONE IONIC LIQUID AND A METHOD OF DESENSITIZING AN EXPLOSIVE COMPOSITION | ALLIANT TECHSYSTEMS INC. (US) | 2012-02-02 | — | — | US | claimed |
| US-8012277-B2 | Mixture with activator; desentization melt | ALLIANT TECHSYSTEMS INC. (US) | 2011-09-06 | — | — | US | claimed |
| US-20080251169-A1 | IONIC LIQUID, A METHOD OF SYNTHESIZING AN IONIC LIQUID, A PRECURSOR OF AN EXPLOSIVE COMPOSITION INCLUDING AT LEAST ONE IONIC LIQUID, AND A METHOD OF DESENSITIZING AN EXPLOSIVE COMPOSITION | ALLIANT TECHSYSTEMS INC. (US) | 2008-10-16 | — | — | US | claimed |
| US-12534587-B2 | Thermally expandable compositions comprising a chemical blowing agent | SIKA TECHNOLOGY AG (CH) | 2026-01-27 | — | — | US | disclosed |
| CN-119753848-B | Amino guanidine oxalate second-order nonlinear optical crystal material, preparation and application thereof | 同济大学 | 2025-09-19 | — | — | CN | disclosed |
| CN-119753848-B | Amino guanidine oxalate second-order nonlinear optical crystal material, preparation and application thereof | 同济大学 | 2025-09-19 | — | — | CN | disclosed |
| CN-119753848-A | Amino guanidine oxalate second-order nonlinear optical crystal material, preparation and application thereof | 同济大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119753848-A | Amino guanidine oxalate second-order nonlinear optical crystal material, preparation and application thereof | 同济大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-119753848-A | Amino guanidine oxalate second-order nonlinear optical crystal material, preparation and application thereof | 同济大学 | 2025-04-04 | — | — | CN | disclosed |
| CN-117836271-A | Salts of phenylpyrrolaminoguanidine and polymorphs of phenylpyrrolaminoguanidine onium salts | 西奈克制药有限公司 | 2024-04-05 | — | — | CN | disclosed |
| EP-3156426-A1 | MODIFIED RUBBER FOR TYRE, RUBBER COMPOSITION FOR TYRE USING SAID MODIFIED RUBBER AND TYRE | Mitsubishi Gas Chemical Company, Inc. (JP) | 2017-04-19 | — | — | EP | disclosed |
| CN-106458870-A | Alkyleneaminoguanidine and salt thereof, composition for modification, modified rubber for tire, rubber composition for tire, and tire | 三菱瓦斯化学株式会社 | 2017-02-22 | — | — | CN | disclosed |
| CN-106414508-A | Modified rubber for tyre, rubber composition for tyre using said modified rubber and tyre | 三菱瓦斯化学株式会社 | 2017-02-15 | — | — | CN | disclosed |
| US-8425702-B2 | Precursor of an explosive composition including at least one ionic liquid and a method of desensitizing an explosive composition | ALLIANT TECHSYSTEMS INC. (US) | 2013-04-23 | — | — | US | disclosed |
| US-20120024437-A1 | PRECURSOR OF AN EXPLOSIVE COMPOSITION INCLUDING AT LEAST ONE IONIC LIQUID AND A METHOD OF DESENSITIZING AN EXPLOSIVE COMPOSITION | ALLIANT TECHSYSTEMS INC. (US) | 2012-02-02 | — | — | US | disclosed |
| US-8012277-B2 | Mixture with activator; desentization melt | ALLIANT TECHSYSTEMS INC. (US) | 2011-09-06 | — | — | US | disclosed |
| US-20080251169-A1 | IONIC LIQUID, A METHOD OF SYNTHESIZING AN IONIC LIQUID, A PRECURSOR OF AN EXPLOSIVE COMPOSITION INCLUDING AT LEAST ONE IONIC LIQUID, AND A METHOD OF DESENSITIZING AN EXPLOSIVE COMPOSITION | ALLIANT TECHSYSTEMS INC. (US) | 2008-10-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12534587-B2 | Thermally expandable compositions comprising a chemical blowing agent | OGG1, GRN, TAF1 | TSHR 4739/4885NFKB1 2929/4885CYP1A2 4147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.