Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8496276 | 0.80 | SLC6A3 (0.56) | KMT2AMEN1KDM4ETSHRMAPT | |
| SCHEMBL4012935 | 0.79 | SMN1; SMN2 (0.54) | KMT2AMEN1KDM4ETSHRMAPT | |
| SCHEMBL7049387 | 0.78 | DHODH (0.51) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL3898412 | 0.78 | RAB9A (0.58) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL10476973 | 0.78 | DHODH (0.54) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL6932656 | 0.77 | SLC6A3 (0.55) | KMT2AMEN1KDM4ETSHRMAPT | |
| SCHEMBL18539206 | 0.77 | SLC6A3 (0.59) | KMT2AMEN1KDM4ETSHRMAPT | |
| SCHEMBL29112020 | 0.76 | KMT2A (0.43) | KMT2AMEN1KDM4ENPC1RAB9A | |
| SCHEMBL38662586 | 0.75 | MEN1 (0.71) | KMT2AMEN1KDM4ETSHRMAPT | |
| SCHEMBL2443270 | 0.75 | MEN1 (0.71) | KMT2AMEN1KDM4ETSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074101-A2 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | Siemens Healthcare Diagnostics Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008067055-A2 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-06-05 | — | — | WO | disclosed |