Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4012934 | 0.79 | KMT2A (0.54) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL2443270 | 0.74 | MEN1 (0.71) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL38662586 | 0.74 | MEN1 (0.71) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL14134529 | 0.74 | MAPT (0.56) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL3898415 | 0.71 | KDM4E (0.51) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL27618204 | 0.71 | NPSR1 (0.58) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL10476973 | 0.71 | DHODH (0.54) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL6990716 | 0.71 | FABP4 (0.47) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL28095231 | 0.71 | KMT2A (0.51) | SMN1; SMN2MEN1KMT2ALMNAKDM4E | |
| SCHEMBL7534026 | 0.70 | PDE10A (0.51) | MEN1KMT2ALMNAKDM4EPDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074101-A2 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | Siemens Healthcare Diagnostics Inc. (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008067055-A2 | STABLE ACRIDINIUM ESTERS WITH FAST LIGHT EMISSION | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2008-06-05 | — | — | WO | disclosed |