Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL399137 | 0.97 | KIF11 (0.31) | PPARGNR1H4 | |
| Hydrochloric Acid SCHEMBL398223 | 0.94 | MAPT (0.32) | — | |
| Hydrochloric Acid SCHEMBL399755 | 0.93 | GRM5 (0.32) | GRM5PPARGNR1H4 | |
| Hydrochloric Acid SCHEMBL397055 | 0.92 | PPARG (0.32) | PPARGNR1H4 | |
| Hydrochloric Acid SCHEMBL452699 | 0.92 | NPC1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL400914 | 0.90 | PPARG (0.31) | PPARGNR1H4 | |
| Hydrochloric Acid SCHEMBL5079539 | 0.90 | MEN1 (0.33) | NR1H4 | |
| Fluoride Ion SCHEMBL7641229 | 0.90 | NPC1 (0.31) | — | |
| Hydrochloric Acid SCHEMBL399225 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL401424 | 0.88 | GRM5 (0.30) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8101684-B2 | Thermoplastic resin composition for sealing solar cell, sheet for sealing solar cell and solar cell | MITSUI CHEMICALS, INC. (JP) | 2012-01-24 | — | — | US | disclosed |
| EP-2275457-A2 | Propylene polymer, propylene-based polymer composition, and use of these | Mitsui Chemicals, Inc. (JP) | 2011-01-19 | — | — | EP | disclosed |