Hydrochloric Acid

Hydrochloric Acid

SCHEMBL452699

CC(C)(C)c1ccc2c(c1)C([Zr+2](C1=CC=CC1)=C(c1ccccc1)c1ccccc1)c1cc(C(C)(C)C)ccc1-2.[Cl-].[Cl-]

nearest known ligand 0.31

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 1/20 0.31
ALDH1A1 P00352 1/20 0.31
PLA2G1B P04054 1/20 0.31
NFKB1 P19838 1/20 0.31
CASP3 P42574 1/20 0.31
RAB9A P51151 1/20 0.31
NFKB2 Q00653 1/20 0.31
RELA Q04206 1/20 0.31
SENP8 Q96LD8 1/20 0.31
SENP7 Q9BQF6 1/20 0.31
SENP6 Q9GZR1 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
ATG4B Q9Y4P1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5079539 0.98 MEN1 (0.33) NPC1ALDH1A1RAB9A
Fluoride Ion SCHEMBL7641229 0.98 NPC1 (0.31) NPC1ALDH1A1PLA2G1BNFKB1CASP3
Hydrochloric Acid SCHEMBL5077562 0.95 MEN1 (0.32)
Hydrochloric Acid SCHEMBL397055 0.94 PPARG (0.32)
Hydrochloric Acid SCHEMBL2865688 0.93
Hydrochloric Acid SCHEMBL401315 0.92 GRM5 (0.31)
Hydrochloric Acid SCHEMBL5083617 0.92
Hydrochloric Acid SCHEMBL397052 0.91 ACHE (0.36) ALDH1A1
Hydrochloric Acid SCHEMBL545120 0.91 KCNK9 (0.32) NPC1ALDH1A1PLA2G1BNFKB1CASP3
Hydrochloric Acid SCHEMBL5081107 0.91 NR1H4 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8003739-B2 Multi-component catalyst systems and polymerization processes for forming in-situ heterophasic copolymers and/or varying the xylene solubles content of polyolefins FINA TECHNOLOGY, INC. (US) 2011-08-23 US claimed
US-6207774-B1 COPOLYMERIZATION OF ETHYLENE WITH AN .ALPHA.-OLEFIN HAVING THREE OR MORE CARBONS BY USE OF AN OLEFIN POLYMERIZATION CATALYST CONTAINING A METALLOCENE COMPOUND, AN IONIZING IONIC COMPOUD, AND AN ORGANOALUMINUM COMPOUNDTHE METALLO TOSOH CORPORATION (JP) 2001-03-27 US claimed
WO-2024185503-A1 RESIN MODIFIER AND RESIN COMPOSITION COMPRISING SAME 東ソー株式会社 2024-09-12 WO disclosed
US-11407884-B2 Resin composition and film comprising it TOSOH CORPORATION (JP) 2022-08-09 US disclosed
EP-3020736-B1 ULTRA-HIGH-MOLECULAR-WEIGHT POLYETHYLENE PARTICLES AND MOLDED BODY COMPRISING SAME TOSOH CORP (JP) 2020-09-09 EP disclosed
US-20200095405-A1 RESIN COMPOSITION AND FILM COMPRISING IT TOSOH CORPORATION (JP) 2020-03-26 US disclosed
EP-1661921-B1 Synthetic lubricating oil and lubricating oil composition thereof MITSUI CHEMICALS INC (JP) 2019-07-17 EP disclosed
US-10316119-B2 Ultrahigh molecular weight polyethylene particles and molded product made thereof TOSOH CORPORATION (JP) 2019-06-11 US disclosed
US-9732208-B2 Polyethylene resin composition, laminate comprising same, and medical container using laminate TOSOH CORPORATION (JP) 2017-08-15 US disclosed
US-9714306-B2 Olefin resin and method for producing same MITSUI CHEMICALS, INC. (JP) 2017-07-25 US disclosed
EP-1964860-B1 ETHYLENE POLYMER, CATALYST FOR PRODUCTION OF ETHYLENE POLYMER, AND PROCESS FOR PRODUCTION OF ETHYLENE POLYMER TOSOH CORP (JP) 2017-07-05 EP disclosed
US-6372681-B1 METALLOCENE OF TRANSITION METAL AND; METAL OXIDE, SULFIDE, PHOSPHIDE, CARBIDE, NITRIDE, AND/OR SELENIDE; ORGANOALKALINE EARTH OR ZINC COMPOUND; AND ORGANOALUMINUM COMPOUND TOSOH CORPORATION (JP) 2002-04-16 US disclosed
US-6207774-B1 COPOLYMERIZATION OF ETHYLENE WITH AN .ALPHA.-OLEFIN HAVING THREE OR MORE CARBONS BY USE OF AN OLEFIN POLYMERIZATION CATALYST CONTAINING A METALLOCENE COMPOUND, AN IONIZING IONIC COMPOUD, AND AN ORGANOALUMINUM COMPOUNDTHE METALLO TOSOH CORPORATION (JP) 2001-03-27 US disclosed
EP-0942006-A2 Catalyst for olefin polymer production and process for olefin polymer production employing the catalyst TOSOH CORPORATION (JP) 1999-09-15 EP disclosed
EP-0612769-B1 Process for producing ethylene alpha-olefin copolymer TOSOH CORP (JP) 1997-11-12 EP disclosed
EP-0648786-B1 Process for producing alpha-olefin polymer TOSOH CORP (JP) 1997-07-16 EP disclosed
US-5576259-A POLYMERIZATION CATALYST INCLUDING METALLOCENE COMPOUND, IONIC COMPOUND, ORGANOALUMINUM COMPOUND, AND LEWIS BASE TOSOH CORPORATION (JP) 1996-11-19 US disclosed
EP-0653445-A1 Ethylene/alpha-olefin copolymer Tosoh Corporation (JP) 1995-05-17 EP disclosed
EP-0648786-A1 Process for producing alpha-olefin polymer Tosoh Corporation (JP) 1995-04-19 EP disclosed
EP-0612769-A1 Process for producing ethylene alpha-olefin copolymer TOSOH CORPORATION (JP) 1994-08-31 EP disclosed