Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27792402 | 0.81 | HSD11B1 (0.42) | CYP2C19 | |
| SCHEMBL1892295 | 0.77 | SLC33A1 (0.39) | — | |
| SCHEMBL27771405 | 0.77 | CYP19A1 (0.36) | — | |
| SCHEMBL2871115 | 0.77 | ACHE (0.45) | — | |
| SCHEMBL1892338 | 0.77 | APLNR (0.36) | CYP2C19MAPT | |
| SCHEMBL27771379 | 0.76 | CYP19A1 (0.40) | — | |
| SCHEMBL1895939 | 0.76 | ACHE (0.41) | — | |
| SCHEMBL4313277 | 0.76 | CD274 (0.41) | — | |
| SCHEMBL1890017 | 0.75 | SLC33A1 (0.38) | ALDH1A1 | |
| SCHEMBL1892333 | 0.74 | SLC33A1 (0.57) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |