Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 6/20 | 0.44 |
| ▸ | EDNRA | P25101 | 6/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | DDR1 | Q08345 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14478110 | 0.84 | CA1 (0.51) | EDNRBEDNRATSHRGLASMN1; SMN2 | |
| SCHEMBL11334245 | 0.82 | ALDH1A1 (0.49) | EDNRBEDNRAKMT2ATSHRGLA | |
| SCHEMBL9196907 | 0.79 | EDNRB (0.46) | EDNRBEDNRAKMT2ATSHRGLA | |
| SCHEMBL19416657 | 0.79 | HTT (0.46) | EDNRBEDNRAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL265203 | 0.79 | EDNRB (0.46) | EDNRBEDNRAKMT2ATSHRGLA | |
| SCHEMBL29411241 | 0.78 | TSHR (0.41) | EDNRBEDNRAKMT2ATSHRGLA | |
| SCHEMBL264948 | 0.78 | EDNRB (0.45) | EDNRBEDNRAKMT2ATSHRGLA | |
| SCHEMBL6465 | 0.78 | EDNRB (0.45) | EDNRBEDNRAKMT2ATSHRGLA | |
| SCHEMBL1346608 | 0.78 | CA2 (0.49) | EDNRBEDNRAKMT2AALDH1A1CA1 | |
| Hydrochloric Acid SCHEMBL28847054 | 0.76 | EDNRB (0.44) | EDNRBEDNRAKMT2ATSHRGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101541751-A | Quinoline compounds | WYETH CORP (US) | 2009-09-23 | — | — | CN | disclosed |
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |