Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 3/20 | 0.47 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.39 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1887155 | 0.87 | PPARG (0.48) | ALDH1A1PPARGAGTR1AGTR2ACHE | |
| SCHEMBL4012027 | 0.83 | PPARG (0.63) | ALDH1A1MAPK1PPARGAGTR1AGTR2 | |
| SCHEMBL4010731 | 0.81 | PPARG (0.50) | PPARGAGTR1AGTR2ACHECNR1 | |
| SCHEMBL13625893 | 0.80 | PPARG (0.48) | ALDH1A1PPARGAGTR1AGTR2ACHE | |
| SCHEMBL1889210 | 0.80 | PPARG (0.48) | ALDH1A1PPARGAGTR1AGTR2ACHE | |
| SCHEMBL4009715 | 0.78 | PPARG (0.53) | PPARGAGTR1AGTR2ACHE | |
| SCHEMBL4017757 | 0.77 | PPARG (0.60) | ALDH1A1MAPK1PPARGACHE | |
| SCHEMBL9854355 | 0.77 | PPARG (0.53) | ALDH1A1PPARGAGTR1AGTR2 | |
| SCHEMBL14208362 | 0.75 | PPARG (0.48) | ALDH1A1MAPK1PPARGAGTR1AGTR2 | |
| SCHEMBL9264984 | 0.75 | PPARG (0.43) | PPARGAGTR1AGTR2ACHEGRIA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |