Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.38 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.38 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1889210 | 0.88 | PPARG (0.48) | PPARGACHEDPP4AGTR1AGTR2 | |
| SCHEMBL1887155 | 0.88 | PPARG (0.48) | PPARGACHEDPP4AGTR1AGTR2 | |
| SCHEMBL4010731 | 0.82 | PPARG (0.50) | PPARGACHEDPP4AGTR1AGTR2 | |
| SCHEMBL4013432 | 0.80 | ALDH1A1 (0.49) | PPARGACHEDPP4AGTR1AGTR2 | |
| SCHEMBL9854355 | 0.75 | PPARG (0.53) | PPARGAGTR1AGTR2ALDH1A1LMNA | |
| SCHEMBL9032306 | 0.74 | PPARG (0.42) | PPARGAGTR1AGTR2ALDH1A1 | |
| SCHEMBL9264984 | 0.73 | PPARG (0.43) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL12993894 | 0.73 | PPARG (0.61) | PPARGACHEAGTR1AGTR2 | |
| SCHEMBL9031592 | 0.73 | PPARG (0.44) | PPARGAGTR1AGTR2LMNATP53 | |
| SCHEMBL13368447 | 0.72 | PPARG (0.60) | PPARGACHEAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |