Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.53 |
| ▸ | AGTR1 | P30556 | 2/20 | 0.45 |
| ▸ | AGTR2 | P50052 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9854341 | 0.92 | PPARG (0.54) | PPARGAGTR1AGTR2HPGDALDH1A1 | |
| SCHEMBL8566073 | 0.85 | PPARG (0.61) | PPARGAGTR1AGTR2LMNATP53 | |
| SCHEMBL9853637 | 0.83 | PPARG (0.74) | PPARGAGTR1AGTR2LMNATP53 | |
| SCHEMBL9854386 | 0.82 | PPARG (0.53) | PPARGAGTR1AGTR2LMNAMAPT | |
| SCHEMBL9854319 | 0.81 | BRD4 (0.53) | PPARGAGTR1AGTR2HPGDALDH1A1 | |
| SCHEMBL9851543 | 0.81 | AGTR1 (0.66) | PPARGAGTR1AGTR2ALDH1A1LMNA | |
| SCHEMBL9854370 | 0.79 | AGTR1 (0.51) | AGTR1AGTR2HPGDALDH1A1ATM | |
| SCHEMBL9854307 | 0.79 | PPARG (0.49) | PPARGAGTR1AGTR2LMNARXFP1 | |
| SCHEMBL8874596 | 0.78 | PPARG (0.53) | PPARGAGTR1AGTR2LMNATHRB | |
| SCHEMBL4010731 | 0.77 | PPARG (0.50) | PPARGAGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0426021-A1 | Condensed imidazole derivatives and processes for preparation thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-08 | — | — | EP | disclosed |