Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.69 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
| ▸ | IGF1R | P08069 | 2/20 | 0.34 |
| ▸ | EGFR | P00533 | 1/20 | 0.34 |
| ▸ | INSR | P06213 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3935343 | 0.82 | FAAH (0.89) | FAAHKDRNPC1ALDH1A1RAB9A | |
| SCHEMBL3936220 | 0.82 | FAAH (1.00) | FAAHNPC1RAB9A | |
| SCHEMBL3933752 | 0.82 | FAAH (0.89) | FAAHNPC1RAB9A | |
| SCHEMBL3941123 | 0.81 | FAAH (0.86) | FAAHNPC1RAB9A | |
| SCHEMBL3931765 | 0.81 | FAAH (0.79) | FAAHTRPV1NPC1RAB9AHTR7 | |
| SCHEMBL4022293 | 0.80 | FAAH (0.69) | FAAHKDRKDM4ENPC1ALDH1A1 | |
| SCHEMBL3935112 | 0.80 | FAAH (0.87) | FAAHNPC1LMNARAB9AIGF1R | |
| SCHEMBL3933423 | 0.80 | FAAH (0.87) | FAAHNPC1ALDH1A1RAB9A | |
| SCHEMBL4014452 | 0.79 | FAAH (0.68) | FAAHKDRKDM4ENPC1ALDH1A1 | |
| SCHEMBL4013901 | 0.79 | FAAH (0.70) | FAAHLMNAHTTHTR6GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |