Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.70 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.40 |
| ▸ | PEX14 | O75381 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4014452 | 0.90 | FAAH (0.68) | FAAHHCRTR1HCRTR2LMNAHTT | |
| SCHEMBL3933752 | 0.83 | FAAH (0.89) | FAAH | |
| SCHEMBL3936220 | 0.83 | FAAH (1.00) | FAAH | |
| SCHEMBL3931765 | 0.81 | FAAH (0.79) | FAAHDRD2DRD4DRD3GRM4 | |
| SCHEMBL3935343 | 0.81 | FAAH (0.89) | FAAH | |
| SCHEMBL4017197 | 0.81 | FAAH (0.75) | FAAHGRM4 | |
| SCHEMBL3933423 | 0.81 | FAAH (0.87) | FAAH | |
| SCHEMBL3935112 | 0.81 | FAAH (0.87) | FAAHLMNA | |
| SCHEMBL3941123 | 0.80 | FAAH (0.86) | FAAH | |
| SCHEMBL4012669 | 0.79 | FAAH (0.79) | FAAHHTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |