Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4013550 | 0.93 | FAAH (0.61) | FAAHNPC1KMT2AMEN1NAMPT | |
| SCHEMBL4015735 | 0.92 | FAAH (0.61) | FAAHNPC1KMT2AMEN1NAMPT | |
| SCHEMBL4013961 | 0.91 | FAAH (0.58) | FAAHNPC1KMT2AMEN1NAMPT | |
| SCHEMBL4010011 | 0.89 | FAAH (0.59) | FAAHNPC1KMT2AMEN1NAMPT | |
| SCHEMBL4011606 | 0.85 | FAAH (0.67) | FAAHNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4012448 | 0.85 | FAAH (0.57) | FAAHNPC1KMT2AMEN1NAMPT | |
| SCHEMBL4012253 | 0.82 | FAAH (0.68) | FAAHNPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL4015901 | 0.79 | FAAH (0.67) | FAAHNPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL3941492 | 0.77 | FAAH (0.59) | FAAHNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3941343 | 0.77 | FAAH (0.86) | FAAHKMT2AMEN1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |