Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 13/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4011606 | 0.90 | FAAH (0.67) | FAAHPTGDR2NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL4013550 | 0.89 | FAAH (0.61) | FAAHPTGDR2NPC1KDM4ESMN1; SMN2 | |
| SCHEMBL4013486 | 0.85 | FAAH (0.60) | FAAHNPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL4015735 | 0.85 | FAAH (0.61) | FAAHNPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL4010011 | 0.84 | FAAH (0.59) | FAAHNPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL4013961 | 0.83 | FAAH (0.58) | FAAHNPC1MEN1KMT2ANAMPT | |
| SCHEMBL4012253 | 0.82 | FAAH (0.68) | FAAHNPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL3935486 | 0.82 | FAAH (0.77) | FAAH | |
| SCHEMBL4015901 | 0.79 | FAAH (0.67) | FAAHNPC1KDM4ESMN1; SMN2HSD17B10 | |
| SCHEMBL4020374 | 0.78 | FAAH (0.54) | FAAHNPC1KDM4ESMN1; SMN2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |