Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 11/20 | 0.68 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3941492 | 0.86 | FAAH (0.59) | FAAHNPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4019524 | 0.85 | FAAH (0.78) | FAAHNPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4015901 | 0.84 | FAAH (0.67) | FAAHNPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4013550 | 0.83 | FAAH (0.61) | FAAHNPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4012855 | 0.83 | FAAH (0.79) | FAAHNPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4012448 | 0.82 | FAAH (0.57) | FAAHNPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4011606 | 0.82 | FAAH (0.67) | FAAHNPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4013486 | 0.82 | FAAH (0.60) | FAAHNPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4015735 | 0.82 | FAAH (0.61) | FAAHNPC1KDM4ESMN1; SMN2RAB9A | |
| SCHEMBL4020374 | 0.82 | FAAH (0.54) | FAAHNPC1KDM4ESMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009011904-A1 | COMPOUNDS USEFUL AS FAAH MODULATORS AND USES THEREOF | RENOVIS, INC. (US) | 2009-01-22 | — | — | WO | disclosed |