Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 9/20 | 0.38 |
| ▸ | CNR2 | P34972 | 9/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009317 | 0.88 | CNR1 (0.40) | ALDH1A1MAPTCNR1CNR2CYP1A2 | |
| SCHEMBL4007963 | 0.88 | CNR1 (0.42) | CNR1CNR2 | |
| SCHEMBL4014170 | 0.86 | MAPT (0.43) | ALDH1A1LMNAMAPTTDP1CYP1A2 | |
| SCHEMBL4010115 | 0.85 | MAPT (0.39) | ALDH1A1LMNAMAPTTDP1CNR1 | |
| SCHEMBL4007693 | 0.84 | CNR1 (0.42) | ALDH1A1LMNACNR1CNR2CYP1A2 | |
| SCHEMBL8021652 | 0.84 | CYP1A2 (0.42) | ALDH1A1LMNAMAPTTDP1CNR1 | |
| SCHEMBL4010260 | 0.84 | ATM (0.45) | ALDH1A1LMNAMAPTTDP1CYP1A2 | |
| SCHEMBL4008643 | 0.81 | MAPT (0.46) | ALDH1A1LMNAMAPTTDP1CYP1A2 | |
| SCHEMBL4007961 | 0.80 | CNR1 (0.43) | CNR1CNR2 | |
| SCHEMBL4008512 | 0.78 | MAPT (0.42) | ALDH1A1LMNAMAPTTDP1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |