Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4009317 | 0.96 | CNR1 (0.40) | CNR1CNR2KCNH2SIGMAR1CYP1A2 | |
| SCHEMBL4014101 | 0.84 | ALDH1A1 (0.41) | CNR1CNR2LMNACYP1A2POLB | |
| SCHEMBL8040695 | 0.84 | CNR1 (0.46) | CNR1CNR2LMNACYP1A2POLB | |
| SCHEMBL8037790 | 0.80 | CNR1 (0.46) | CNR1CNR2KCNH2SIGMAR1POLB | |
| SCHEMBL4011709 | 0.80 | MAPT (0.41) | KCNH2SIGMAR1LMNACYP1A2POLB | |
| SCHEMBL8031451 | 0.79 | KDM4E (0.46) | CNR1LMNACYP1A2POLBRAB9A | |
| SCHEMBL8034897 | 0.76 | KDM4E (0.46) | CNR1CNR2KCNH2SIGMAR1POLB | |
| SCHEMBL4010115 | 0.74 | MAPT (0.39) | CNR1LMNACYP1A2POLBRAB9A | |
| SCHEMBL4009770 | 0.73 | MAPT (0.37) | KCNH2SIGMAR1LMNACYP1A2POLB | |
| SCHEMBL4011731 | 0.72 | MAPT (0.41) | LMNACYP1A2RAB9ANPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |