Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | DHPS | P49366 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008889 | 0.88 | DHPS (0.41) | MAPTLMNAALDH1A1TDP1DHPS | |
| SCHEMBL4010260 | 0.87 | ATM (0.45) | MAPTLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL4014101 | 0.86 | ALDH1A1 (0.41) | MAPTLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL4008643 | 0.85 | MAPT (0.46) | MAPTLMNAALDH1A1TDP1DHPS | |
| SCHEMBL4010263 | 0.84 | DHPS (0.41) | MAPTLMNAALDH1A1TDP1DHPS | |
| SCHEMBL8034434 | 0.83 | LMNA (0.44) | MAPTLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL4010115 | 0.82 | MAPT (0.39) | MAPTLMNAALDH1A1TDP1CYP1A2 | |
| SCHEMBL4008512 | 0.81 | MAPT (0.42) | MAPTLMNAALDH1A1TDP1DHPS | |
| SCHEMBL4011709 | 0.81 | MAPT (0.41) | MAPTLMNAALDH1A1TDP1DHPS | |
| SCHEMBL4008885 | 0.79 | FABP3 (0.41) | MAPTLMNAALDH1A1TDP1DHPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |