Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4008547 | 0.86 | GRIK1 (0.36) | GRIK1MAPTHPGD | |
| SCHEMBL5097736 | 0.80 | MMP1 (0.30) | — | |
| SCHEMBL5097737 | 0.80 | MMP1 (0.30) | — | |
| SCHEMBL4010131 | 0.77 | SMN1; SMN2 (0.30) | MAPT | |
| SCHEMBL9268644 | 0.76 | ALDH1A1 (0.33) | MAPT | |
| SCHEMBL7100682 | 0.73 | MAPT (0.30) | MAPT | |
| SCHEMBL7104542 | 0.73 | MAPT (0.32) | MAPTHPGD | |
| SCHEMBL7104544 | 0.73 | MAPT (0.32) | MAPTHPGD | |
| SCHEMBL7100684 | 0.73 | MAPT (0.30) | MAPT | |
| SCHEMBL4011240 | 0.73 | TSHR (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009080248-A1 | SUBSTITUTED 2-PHENYLPYRIMIDINE-5-CARBOXYLIC ACIDS AND THE USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-07-02 | — | — | WO | disclosed |