Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.39 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.39 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 4/20 | 0.39 |
| ▸ | SENP3 | Q9H4L4 | 2/20 | 0.39 |
| ▸ | MPL | P40238 | 6/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.37 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.36 |
| ▸ | ATIC | P31939 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CTRC | Q99895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14566372 | 0.87 | MEN1 (0.55) | MEN1KMT2ASENP2SUMO2SUMO1 | |
| SCHEMBL136734 | 0.81 | MEN1 (0.44) | MEN1KMT2ASENP2SUMO2SUMO1 | |
| SCHEMBL14695213 | 0.80 | MEN1 (0.43) | MEN1KMT2AALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL101050 | 0.77 | MEN1 (0.49) | MEN1KMT2ASENP2SUMO2SUMO1 | |
| SCHEMBL4255042 | 0.77 | MPL (0.40) | MEN1KMT2ASENP2SUMO2SUMO1 | |
| SCHEMBL4020207 | 0.77 | MEN1 (0.54) | MEN1KMT2ATTR | |
| SCHEMBL14958133 | 0.76 | MEN1 (0.52) | MEN1KMT2ASENP2SUMO2SUMO1 | |
| SCHEMBL4014873 | 0.76 | MEN1 (0.47) | MEN1KMT2ASENP2SUMO2SUMO1 | |
| SCHEMBL2957950 | 0.75 | MEN1 (0.45) | MEN1KMT2A | |
| SCHEMBL135180 | 0.75 | MEN1 (0.36) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2576699-B1 | NAPHTHOCYANINES FOR USE AS CONTRAST AGENTS | PHARMPUR GMBH (DE) | 2017-07-12 | — | — | EP | disclosed |
| US-8835484-B2 | Naphthocyanines for use as contrast agents | ALAMEDICS GMBH & CO. KG (DE) | 2014-09-16 | — | — | US | disclosed |
| US-20130131354-A1 | Naphthocyanines for Use as Contrast Agents | AIAMEDICS GmbH & Co. KG (DE) | 2013-05-23 | — | — | US | disclosed |
| EP-2576699-A1 | NAPHTHOCYANINES FOR USE AS CONTRAST AGENTS | ALAMEDICS GMBH & CO. KG (DE) | 2013-04-10 | — | — | EP | disclosed |
| EP-1165693-A2 | SQUARAINE DYES | Amersham Pharmacia Biotech UK Limited (GB) | 2002-01-02 | — | — | EP | disclosed |
| WO-2000058405-A2 | SQUARAINE DYES | AMERSHAM PHARMACIA BIOTECH UK LIMITED (GB) | 2000-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130131354-A1 | Naphthocyanines for Use as Contrast Agents | NPM1, UACA, INCENP | MEN1 314/4885KMT2A 3765/4885SENP2 4371/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.