Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.45 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19889199 | 0.94 | MAPT (0.54) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL1313679 | 0.80 | FKBP1A (0.62) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL19889201 | 0.79 | TDP1 (0.54) | ALDH1A1KDM4EHSD17B10MAPTSMN1; SMN2 | |
| SCHEMBL18292117 | 0.75 | FKBP1A (0.50) | ALDH1A1KDM4EHPGDHSD17B10MAPT | |
| SCHEMBL28308417 | 0.74 | MAPT (0.58) | ALDH1A1KDM4EMAPTSMN1; SMN2TDP1 | |
| SCHEMBL16294097 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KDM4EHSD17B10KMT2ARAB9A | |
| SCHEMBL1066335 | 0.74 | SMN1; SMN2 (0.61) | ALDH1A1MAPTSMN1; SMN2TDP1LIN28A | |
| SCHEMBL1313160 | 0.73 | SMN1; SMN2 (0.56) | ALDH1A1KDM4EHPGDHSD17B10SMN1; SMN2 | |
| SCHEMBL16626904 | 0.72 | SMN1; SMN2 (0.59) | MAPTSMN1; SMN2TDP1LIN28AKMT2A | |
| SCHEMBL16626907 | 0.72 | SMN1; SMN2 (0.59) | ALDH1A1MAPTSMN1; SMN2TDP1LIN28A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | claimed |
| WO-2009084737-A1 | COMPOUND HAVING ACTIVITY TO SUPPRESS DEGRANULATION AND CYTOKINE PRODUCTION AND USE THEREOF | INTERPROTEIN CORPORATION (JP) | 2009-07-09 | — | — | WO | disclosed |