Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 7/20 | 0.44 |
| ▸ | HTR2A | P28223 | 6/20 | 0.44 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.44 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.44 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.44 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.44 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.44 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 4/20 | 0.44 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | COMT | P21964 | 1/20 | 0.42 |
| ▸ | GPR6 | P46095 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28875078 | 0.93 | HTR2C (0.47) | DRD2HTR2CHTR2APSEN1PSEN2 | |
| SCHEMBL12184749 | 0.85 | HTR2C (0.51) | HTR2CHTR2APSEN1PSEN2APH1B | |
| Hydrochloric Acid SCHEMBL20524629 | 0.83 | HTR2C (0.50) | HTR2CHTR2APSEN1PSEN2APH1B | |
| SCHEMBL15624597 | 0.83 | FFAR4 (0.47) | DRD2HTR2CHTR2APSEN1PSEN2 | |
| SCHEMBL14648626 | 0.79 | LMNA (0.55) | DRD2HTR6ALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL12334568 | 0.79 | MBTD1 (0.49) | DRD2HTR2AHTR6FFAR4 | |
| SCHEMBL4628305 | 0.79 | DRD2 (0.47) | DRD2HTR2CHTR2AFFAR4KCNH2 | |
| SCHEMBL19707178 | 0.79 | DRD2 (0.47) | DRD2HTR6FFAR4POLBCOMT | |
| SCHEMBL2423283 | 0.78 | CA1 (0.51) | DRD2POLB | |
| SCHEMBL29951042 | 0.78 | DRD2 (0.44) | DRD2FFAR4ALDH1A1COMT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074098-A2 | QUINOLINE COMPOUNDS | Wyeth (US) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008049047-A2 | QUINOLINE COMPOUNDS | WYETH (US) | 2008-04-24 | — | — | WO | disclosed |