Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PLIN5 | Q00G26 | 1/20 | 0.40 |
| ▸ | ABHD5 | Q8WTS1 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7323206 | 0.90 | ALDH1A1 (0.48) | CASP1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL17156294 | 0.85 | ALDH1A1 (0.47) | CASP1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL6839231 | 0.84 | KMT2A (0.50) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL20480333 | 0.83 | PIN1 (0.41) | ALDH1A1MAPTKMT2AMEN1NPC1 | |
| SCHEMBL20480529 | 0.80 | PPARG (0.50) | ALDH1A1MAPTKMT2AMEN1LMNA | |
| SCHEMBL6959131 | 0.79 | TDP1 (0.48) | ALDH1A1MAPTKMT2AMEN1HPGD | |
| SCHEMBL901851 | 0.77 | ALDH1A1 (0.46) | CASP1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL10899719 | 0.77 | PPARA (0.47) | ALDH1A1MAPTHPGDGAATDP1 | |
| SCHEMBL901585 | 0.74 | PPARG (0.48) | CASP1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL26022261 | 0.74 | ALDH1A1 (0.48) | ALDH1A1MAPTKMT2AMEN1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085256-A1 | ANTI-HIV COMPOUNDS | PANACOS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |