SCHEMBL4016201

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4015221	0.86	KDR (0.61)	ALDH1A1NAMPTKDRFLT1NPC1
	SCHEMBL4020820	0.85	KDR (0.61)	MAPK1NAMPTKDRFLT1NR3C1
	SCHEMBL4018837	0.84	KDR (0.58)	ALDH1A1NAMPTKDRFLT1CYP1A2
	SCHEMBL4019335	0.81	MAPT (0.49)	LMNATP53MAPK1KDRFLT1
	SCHEMBL4018400	0.79	KDR (0.71)	ALDH1A1LMNATP53MAPK1NAMPT
	SCHEMBL4018180	0.79	KDR (0.50)	KDRFLT1NPC1RAB9ASMN1; SMN2
	SCHEMBL4020039	0.78	RAB9A (0.53)	ALDH1A1LMNATP53MAPK1NPC1
	SCHEMBL4017944	0.78	KDR (0.72)	ALDH1A1LMNATP53MAPK1NAMPT
	SCHEMBL4022539	0.75	MEN1 (0.41)	ALDH1A1LMNATP53FLT1SMN1; SMN2
	SCHEMBL4021062	0.75	LMNA (0.56)	ALDH1A1LMNATP53MAPK1NAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.