Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 14/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016474 | 0.95 | PPARG (0.45) | PPARGKCNH2LTB4R2 | |
| SCHEMBL4010282 | 0.88 | PPARG (0.43) | PPARGKCNH2LTB4R2 | |
| SCHEMBL4016049 | 0.86 | PPARG (0.43) | PPARGKCNH2LTB4R2 | |
| SCHEMBL4158457 | 0.83 | LTB4R2 (0.45) | PPARGLTB4R2 | |
| SCHEMBL4014474 | 0.81 | LTB4R2 (0.49) | PPARGKCNH2LTB4R2 | |
| SCHEMBL1896460 | 0.75 | PPARG (0.70) | PPARGKCNH2 | |
| SCHEMBL4016389 | 0.75 | PPARG (0.58) | PPARGKCNH2 | |
| SCHEMBL1893693 | 0.74 | PPARG (0.70) | PPARGKCNH2 | |
| SCHEMBL4008051 | 0.73 | SLC33A1 (0.47) | — | |
| SCHEMBL1890861 | 0.73 | PPARG (0.64) | PPARGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |