Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 11/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | SLC33A1 | O00400 | 1/20 | 0.42 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016392 | 0.95 | PPARG (0.47) | PPARGKCNH2LTB4R2 | |
| SCHEMBL4010282 | 0.92 | PPARG (0.43) | PPARGKCNH2AGTR1LTB4R2 | |
| SCHEMBL4016049 | 0.88 | PPARG (0.43) | PPARGKCNH2AGTR1LTB4R2 | |
| SCHEMBL4158457 | 0.78 | LTB4R2 (0.45) | PPARGAGTR1SLC33A1LTB4R2 | |
| SCHEMBL4014474 | 0.77 | LTB4R2 (0.49) | PPARGKCNH2AGTR1LTB4R2 | |
| SCHEMBL4011200 | 0.76 | LTB4R2 (0.42) | PPARGSLC33A1LTB4R2 | |
| SCHEMBL4008051 | 0.74 | SLC33A1 (0.47) | AGTR1SLC33A1 | |
| SCHEMBL1890861 | 0.74 | PPARG (0.64) | PPARGKCNH2AGTR1 | |
| SCHEMBL4016469 | 0.74 | PPARG (0.52) | PPARGKCNH2AGTR1SLC33A1 | |
| SCHEMBL4016610 | 0.74 | SLC33A1 (0.46) | AGTR1SLC33A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | claimed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | claimed |
| WO-2009133970-A1 | CRYSTALLINE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2009-11-05 | — | — | WO | disclosed |