Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.40 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017359 | 0.88 | MEN1 (0.49) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL4019849 | 0.87 | MEN1 (0.44) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL4016848 | 0.87 | MEN1 (0.44) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL4017528 | 0.86 | MEN1 (0.49) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL4015839 | 0.85 | MEN1 (0.44) | KMT2AMEN1HDAC4ALDH1A1PTGS2 | |
| SCHEMBL4015068 | 0.85 | MEN1 (0.44) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL4669256 | 0.85 | MEN1 (0.41) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL13982583 | 0.84 | MEN1 (0.48) | KMT2AMEN1HDAC3HDAC4HDAC1 | |
| SCHEMBL4017825 | 0.84 | MMP1 (0.50) | KMT2AMEN1HDAC4ALDH1A1POLB | |
| SCHEMBL4017819 | 0.84 | MEN1 (0.47) | KMT2AMEN1HDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014287-A1 | Use of cinnamic acid derivatives as modulators of an EP2 receptor | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-2014287-A1 | Use of cinnamic acid derivatives as modulators of an EP2 receptor | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | disclosed |