Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4668484 | 0.89 | MEN1 (0.44) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4016407 | 0.85 | KMT2A (0.46) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4017528 | 0.84 | MEN1 (0.49) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4669466 | 0.84 | MEN1 (0.39) | MEN1KMT2AHDAC1HDAC4HDAC6 | |
| SCHEMBL4669463 | 0.84 | MEN1 (0.39) | MEN1KMT2AHDAC1HDAC4HDAC6 | |
| SCHEMBL4017359 | 0.82 | MEN1 (0.49) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL13982460 | 0.82 | MEN1 (0.47) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4752215 | 0.82 | MEN1 (0.43) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4668502 | 0.82 | MEN1 (0.43) | MEN1KMT2AHDAC1HDAC4HDAC3 | |
| SCHEMBL4015839 | 0.82 | MEN1 (0.44) | MEN1KMT2AHDAC4MAPTMEF2D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |