Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017359 | 0.94 | MEN1 (0.49) | MEN1KMT2AGAALMNANPC1 | |
| SCHEMBL13982583 | 0.92 | MEN1 (0.48) | MEN1KMT2AGAALMNANPC1 | |
| SCHEMBL4017822 | 0.91 | GAA (0.55) | MEN1KMT2AGAALMNANPC1 | |
| SCHEMBL13982460 | 0.91 | MEN1 (0.47) | MEN1KMT2AGAALMNANPC1 | |
| SCHEMBL4017825 | 0.90 | MMP1 (0.50) | MEN1KMT2ALMNANPC1RAB9A | |
| SCHEMBL4755471 | 0.89 | MEN1 (0.46) | MEN1KMT2AGAALMNANPC1 | |
| SCHEMBL4669261 | 0.89 | ALDH1A1 (0.48) | MEN1KMT2AGAALMNANPC1 | |
| SCHEMBL4017363 | 0.89 | MEN1 (0.62) | MEN1KMT2AGAALMNANPC1 | |
| SCHEMBL4669267 | 0.89 | MEN1 (0.46) | MEN1KMT2AGAALMNANPC1 | |
| SCHEMBL4667926 | 0.88 | MEN1 (0.45) | MEN1KMT2AGAALMNANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2014287-A1 | Use of cinnamic acid derivatives as modulators of an EP2 receptor | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | claimed |
| EP-2014287-A1 | Use of cinnamic acid derivatives as modulators of an EP2 receptor | Bayer Schering Pharma Aktiengesellschaft (DE) | 2009-01-14 | — | — | EP | disclosed |