Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSPB1 | P04792 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.53 |
| ▸ | CA2 | P00918 | 3/20 | 0.53 |
| ▸ | CES1 | P23141 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | ACHE | P22303 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL134332 | 0.80 | HSPB1 (0.79) | HSPB1CA1CA2CES1CA9 | |
| SCHEMBL2011179 | 0.80 | HSPB1 (0.79) | HSPB1CA1CA2CES1CA9 | |
| SCHEMBL11689190 | 0.80 | HSPB1 (0.79) | HSPB1CA1CA2CES1CA9 | |
| SCHEMBL9183872 | 0.80 | HSPB1 (0.79) | HSPB1CA1CA2CES1CA9 | |
| SCHEMBL27909482 | 0.79 | ALDH1A1 (0.72) | CA1CA2CES1CA9ALDH1A1 | |
| SCHEMBL22567 | 0.79 | ALDH1A1 (0.72) | CA1CA2CES1CA9ALDH1A1 | |
| 4,4'-Oxybis(Nitrobenzene) SCHEMBL8934595 | 0.78 | HSPB1 (0.76) | HSPB1CA1CA2CES1CA9 | |
| SCHEMBL6918525 | 0.76 | HSPB1 (0.55) | HSPB1CA1CA2CES1CA9 | |
| SCHEMBL16906245 | 0.76 | HSPB1 (0.55) | HSPB1CA1CA2CES1CA9 | |
| SCHEMBL9808021 | 0.76 | CYP19A1 (0.54) | ALDH1A1HSD17B10LMNACYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240067824-A1 | SULFORHODAMINE PHOSPHORAMIDITE DYES | CEPHEID | 2024-02-29 | — | — | US | disclosed |
| CN-117486861-A | Nitrogen-containing heterocyclic compound, preparation method and application thereof | 索智生物科技（浙江）有限公司 | 2024-02-02 | — | — | CN | disclosed |
| WO-2017167183-A1 | DIARYL-Β-LACTAM COMPOUND AND PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF | 复旦大学 | 2017-10-05 | — | — | WO | disclosed |
| CN-106830279-A | A kind of processing method and processing device of nitrobenzene waste water | 中国石油天然气集团公司 | 2017-06-13 | — | — | CN | disclosed |
| WO-2017027687-A1 | FUMAGILLOL SPIROCYCLIC COMPOUNDS AND FUSED BICYCLIC COMPOUNDS AND THEIR USE AS METAP2 INHIBITORS | ZAFGEN, INC. (US) | 2017-02-16 | — | — | WO | disclosed |
| WO-2015066053-A2 | TARGETED THERAPEUTICS | SYNTA PHARMACEUTICALS CORP. (US) | 2015-05-07 | — | — | WO | disclosed |
| WO-2015038649-A1 | TARGETED THERAPEUTICS | SYNTA PHARMACEUTICALS CORP. (US) | 2015-03-19 | — | — | WO | disclosed |
| WO-2014151147-A1 | COMBINATION OF KINASE INHIBITORS AND USES THEREOF | INTELLIKINE, LLC (US) | 2014-09-25 | — | — | WO | disclosed |
| WO-2013158644-A2 | TARGETED THERAPEUTICS | SYNTA PHARMACEUTICALS CORP. (US) | 2013-10-24 | — | — | WO | disclosed |
| EP-2044081-A2 | IMPROVED OXIDATION PROCESS WITH ENHANCED SAFETY USEFUL IN THE MANUFACTURE OF MOXIDECTIN BY MEANS OF STABILISED 2-IODOXYBENZOIC ACID (SIBX) | Wyeth (US) | 2009-04-08 | — | — | EP | disclosed |
| WO-2007149305-A2 | IMPROVED OXIDATION PROCESS WITH ENHANCED SAFETY USEFUL IN THE MANUFACTURE OF MOXIDECTIN BY MEANS OF STABILISED 2-IODOXYBENZOIC ACID (SIBX) | WYETH (US) | 2007-12-27 | — | — | WO | disclosed |
| EP-0313474-A2 | An optical article exhibiting a high level of second order polarization susceptibility | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-04-26 | — | — | EP | disclosed |
| US-4051186-A | AMINO-PROPRANOLOL | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1977-09-27 | — | — | US | disclosed |