SCHEMBL4016809

SCHEMBL4016809

CCCCCc1cc(C(=O)O)no1

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 1/20 0.60
HCAR2 Q8TDS4 3/20 0.51
HCAR3 P49019 2/20 0.51
RAB9A P51151 6/20 0.48
SMN1; SMN2 Q16637 5/20 0.48
NPC1 O15118 5/20 0.48
ALDH1A1 P00352 1/20 0.47
POLB P06746 1/20 0.47
HPGD P15428 1/20 0.47
HDAC3 O15379 2/20 0.44
S1PR1 P21453 2/20 0.43
S1PR3 Q99500 2/20 0.43
TSHR P16473 1/20 0.43
XBP1 P17861 1/20 0.43
NPSR1 Q6W5P4 1/20 0.43
RIPK1 Q13546 1/20 0.43
HDAC1 Q13547 1/20 0.43
HDAC2 Q92769 1/20 0.43
HDAC10 Q969S8 1/20 0.43
HDAC6 Q9UBN7 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11722901 0.98 PPARA (0.62) PPARAHCAR2HCAR3RAB9ASMN1; SMN2
SCHEMBL7501852 0.98 PPARA (0.62) PPARAHCAR2HCAR3RAB9ASMN1; SMN2
SCHEMBL11717092 0.98 PPARA (0.62) PPARAHCAR2HCAR3RAB9ASMN1; SMN2
SCHEMBL11721077 0.95 PPARA (0.54) PPARAHCAR2HCAR3RAB9ASMN1; SMN2
SCHEMBL3771944 0.87 RAB9A (0.58) RAB9ASMN1; SMN2NPC1ALDH1A1POLB
SCHEMBL4024862 0.86 PPARA (0.56) PPARARAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL27275588 0.85 PPARA (0.55) PPARARAB9ASMN1; SMN2NPC1ALDH1A1
SCHEMBL4033814 0.85 PPARA (0.58) PPARAHCAR2RAB9ASMN1; SMN2NPC1
SCHEMBL17288448 0.83 PPARA (0.46) PPARAHCAR2RAB9ASMN1; SMN2NPC1
SCHEMBL17288997 0.83 PPARA (0.46) PPARAHCAR2RAB9ASMN1; SMN2NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106659161-B Amide compound and its harmful arthropod prevent and kill off purposes 住友化学株式会社 2019-08-02 CN disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
EP-2952096-B1 Amide compound, an arthropod pest control agent and a method for controlling arthropod pest SUMITOMO CHEMICAL CO (JP) 2018-04-04 EP disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
US-9814235-B2 Method for controlling arthropod pest SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2017-11-14 US disclosed
EP-2952096-A1 METHOD FOR CONTROLLING ARTHROPOD PEST Sumitomo Chemical Company, Limited (JP) 2015-12-09 EP disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-12-03 US disclosed
WO-2014119696-A1 METHOD FOR CONTROLLING ARTHROPOD PEST 住友化学株式会社 (JP) 2014-08-07 WO disclosed
US-20090069288-A1 Novel therapeutic compounds ABBVIE INC. 2009-03-12 US disclosed
WO-2009011850-A2 NOVEL THERAPEUTIC COMPOUNDS ABBOTT LABORATORIES (US) 2009-01-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150344466-A1 METHOD FOR CONTROLLING ARTHROPOD PEST H1-0, H1-3, H1-2 PPARA 2925/4885HCAR2 816/4885HCAR3 704/4885
US-20090069288-A1 Novel therapeutic compounds MAP3K20, RPS6KB1, MAP3K1 PPARA 2138/4885HCAR2 2999/4885HCAR3 2989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.