Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 9/20 | 0.48 |
| ▸ | NPC1 | O15118 | 7/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4033814 | 0.98 | PPARA (0.58) | PPARASMN1; SMN2RAB9ANPC1MAPK1 | |
| SCHEMBL4030288 | 0.95 | SMN1; SMN2 (0.50) | PPARASMN1; SMN2RAB9ANPC1MAPK1 | |
| SCHEMBL4033216 | 0.87 | SMN1; SMN2 (0.60) | SMN1; SMN2RAB9ANPC1MAPK1ALDH1A1 | |
| SCHEMBL4016809 | 0.86 | PPARA (0.60) | PPARASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL27275588 | 0.85 | PPARA (0.55) | PPARASMN1; SMN2RAB9ANPC1MAPK1 | |
| SCHEMBL11722901 | 0.85 | PPARA (0.62) | PPARASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL7501852 | 0.85 | PPARA (0.62) | PPARASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL11717092 | 0.85 | PPARA (0.62) | PPARASMN1; SMN2RAB9ANPC1ALDH1A1 | |
| SCHEMBL4551138 | 0.82 | SMN1; SMN2 (0.54) | PPARASMN1; SMN2RAB9ANPC1MAPK1 | |
| SCHEMBL4551128 | 0.81 | PPARA (0.51) | PPARASMN1; SMN2RAB9ANPC1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060247288-A1 | Method for manufacturing isoxazole derivative or dihydroisoxazole derivative | GAKUIN, RIKKYO (JP) | 2006-11-02 | — | — | US | claimed |
| US-7495107-B2 | Method for manufacturing isoxazole derivative or dihydroisoxazole derivative | RIKKYO GAKUIN (JP) | 2009-02-24 | — | — | US | disclosed |
| US-20060247288-A1 | Method for manufacturing isoxazole derivative or dihydroisoxazole derivative | GAKUIN, RIKKYO (JP) | 2006-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060247288-A1 | Method for manufacturing isoxazole derivative or dihydroisoxazole derivative | CYP3A7, NDUFS7, IDH3A | PPARA 4148/4885SMN1; SMN2 4090/4885RAB9A 4172/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.