Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | LTB4R | Q15722 | 3/20 | 0.44 |
| ▸ | LTB4R2 | Q9NPC1 | 3/20 | 0.44 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.43 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.43 |
| ▸ | MLYCD | O95822 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7458715 | 0.84 | MLYCD (0.50) | KMT2AL3MBTL1LTB4RLTB4R2NPY5R | |
| SCHEMBL4018256 | 0.82 | KMT2A (0.43) | ALDH1A1KMT2AMAPTTDP1LTB4R | |
| SCHEMBL3014165 | 0.81 | LTB4R (0.67) | LTB4RLTB4R2PPARG | |
| SCHEMBL379954 | 0.81 | CYP4A11 (0.50) | ALDH1A1MAPTTDP1CYP1A2CYP2C19 | |
| SCHEMBL379891 | 0.80 | ESRRG (0.47) | ALDH1A1KMT2AMAPTMLYCD | |
| SCHEMBL30264517 | 0.80 | AOC3 (0.51) | ALDH1A1KMT2AL3MBTL1SMN1; SMN2 | |
| SCHEMBL4016939 | 0.80 | KMT2A (0.52) | ALDH1A1PKMKMT2AMAPTTDP1 | |
| SCHEMBL30277846 | 0.79 | ESRRG (0.48) | LTB4RLTB4R2NPY5RMLYCDPDK2 | |
| SCHEMBL2525241 | 0.79 | KMT2A (0.51) | ALDH1A1PKMKMT2AMAPTTDP1 | |
| SCHEMBL3006336 | 0.79 | CA12 (0.45) | ALDH1A1MAPTL3MBTL1CYP1A2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009092796-A1 | SYNEPHRINE DERIVATIVES FOR THE TREATMENT OF CANCER | UNIVERSITEIT GENT (BE) | 2009-07-30 | — | — | WO | claimed |