Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.39 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.39 |
| ▸ | PPARG | P37231 | 3/20 | 0.37 |
| ▸ | RXRA | P19793 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4016960 | 0.87 | MAPK14 (0.41) | AGTR1AGTR2PPARGKMT2A | |
| SCHEMBL1890287 | 0.86 | PPARG (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL12349180 | 0.78 | AGTR1 (0.45) | AGTR1AGTR2 | |
| SCHEMBL1895054 | 0.77 | AGTR1 (0.55) | AGTR1PPARG | |
| SCHEMBL1891957 | 0.76 | AGTR1 (0.54) | AGTR1PPARG | |
| SCHEMBL4016260 | 0.75 | PPARG (0.52) | AGTR1PPARG | |
| SCHEMBL4307218 | 0.73 | KDM4E (0.41) | PPARGALDH1A1POLBKMT2A | |
| SCHEMBL12349127 | 0.72 | PPARG (0.54) | AGTR1AGTR2PPARG | |
| SCHEMBL1895269 | 0.71 | PPARG (0.54) | AGTR1PPARG | |
| SCHEMBL1893260 | 0.71 | PPARG (0.51) | AGTR1AGTR2PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074117-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | Takeda Pharmaceutical Company Limited (JP) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008062905-A2 | HETEROMONOCYCLIC COMPOUND AND USE THEREOF | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-05-29 | — | — | WO | disclosed |