SCHEMBL4017013

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4016729	0.85	SIRT2 (0.71)	KMT2ANT5EMAPK1NAMPTKDR
	SCHEMBL11617697	0.80	MAPK1 (1.00)	KMT2ANT5EMAPK1NAMPTMEN1
	SCHEMBL13969431	0.78	RAB9A (0.59)	KMT2ANT5EMAPK1NAMPTMEN1
	SCHEMBL20379941	0.78	NAMPT (1.00)	NAMPT
	SCHEMBL4019971	0.78	KDR (0.78)	KMT2ANT5EMAPK1NAMPTKDR
	SCHEMBL4018200	0.78	KDR (0.78)	KMT2ANT5EMAPK1NAMPTKDR
	SCHEMBL4020375	0.78	KDR (0.61)	KMT2ANT5EMAPK1NAMPTKDR
	SCHEMBL4019386	0.78	KDR (1.00)	KMT2ANT5EMAPK1NAMPTKDR
	SCHEMBL4022408	0.78	KDR (0.61)	KMT2ANT5EMAPK1NAMPTKDR
	SCHEMBL4023950	0.78	KDR (0.71)	KMT2ANT5EMAPK1NAMPTKDR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.