Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA4 | P22748 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2290706 | 0.84 | ALOX5 (0.43) | KDM4EALOX5CA12CA1CA2 | |
| SCHEMBL22070142 | 0.69 | ALOX5 (0.37) | ALOX5TDP1NFKB1NFKB2RELA | |
| SCHEMBL21625542 | 0.69 | ALOX5 (0.39) | ALOX5TDP1NFKB1NFKB2RELA | |
| SCHEMBL2851113 | 0.69 | ALOX5 (0.36) | ALOX5TDP1NFKB1NFKB2RELA | |
| SCHEMBL290383 | 0.65 | PTGER4 (0.48) | KDM4EALOX5CA12CA1CA2 | |
| SCHEMBL196086 | 0.65 | PTGER4 (0.48) | KDM4EALOX5CA12CA1CA2 | |
| SCHEMBL2290699 | 0.65 | KDM4E (0.51) | KDM4EALOX5CA12CA1CA2 | |
| SCHEMBL16048857 | 0.64 | ALOX5 (0.47) | KDM4EALOX5CA12CA1CA2 | |
| SCHEMBL16048858 | 0.64 | ALOX5 (0.47) | KDM4EALOX5CA12CA1CA2 | |
| SCHEMBL28238937 | 0.63 | CA1 (0.45) | KDM4EALOX5CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1352637-B1 | HAIR GROWTH INHIBITORS AND COMPOSITIONS CONTAINING THE SAME | SHISEIDO CO LTD (JP) | 2009-07-01 | — | — | EP | disclosed |
| US-7285294-B2 | Hair growth inhibitors and composition containing same | SHISEIDO COMPANY, LTD. (JP) | 2007-10-23 | — | — | US | disclosed |
| US-20050175576-A1 | Hair growth inhibitors and composition containing same | SHISEIDO CO., LTD. (JP) | 2005-08-11 | — | — | US | disclosed |
| US-20040047833-A1 | Hair growth inhibitors and compositions containing the same | SHISEIDO COMPANY, LTD. (JP) | 2004-03-11 | — | — | US | disclosed |
| EP-1352637-A1 | HAIR GROWTH INHIBITORS AND COMPOSITIONS CONTAINING THE SAME | SHISEIDO COMPANY LIMITED (JP) | 2003-10-15 | — | — | EP | disclosed |