Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.30 |
| ▸ | TAB1 | Q15750 | 1/20 | 0.30 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22070142 | 0.82 | ALOX5 (0.37) | ALOX5LMNATDP1NFKB1NFKB2 | |
| SCHEMBL21625542 | 0.81 | ALOX5 (0.39) | ALOX5LMNATDP1NFKB1NFKB2 | |
| SCHEMBL2290706 | 0.79 | ALOX5 (0.43) | ALOX5LMNANFKB1NFKB2RELA | |
| SCHEMBL28460175 | 0.70 | LMNA (0.49) | LMNATDP1AKR1B10AKR1B1 | |
| SCHEMBL4017041 | 0.69 | KDM4E (0.34) | ALOX5TDP1NFKB1NFKB2RELA | |
| SCHEMBL910611 | 0.64 | MAP3K7 (0.39) | LMNATDP1MAP3K7TAB1 | |
| SCHEMBL5505151 | 0.62 | CA12 (0.37) | LMNATDP1 | |
| SCHEMBL536156 | 0.61 | LMNA (0.57) | LMNATDP1AKR1B10AKR1B1 | |
| SCHEMBL536158 | 0.61 | LMNA (0.57) | LMNATDP1AKR1B10AKR1B1 | |
| SCHEMBL27632834 | 0.61 | LMNA (0.57) | ALOX5LMNATDP1AKR1B10AKR1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100278760-A1 | Cosmetics | SHISEIDO COMPANY,LTD. (JP) | 2010-11-04 | — | — | US | disclosed |