Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 14/20 | 0.36 |
| ▸ | CNR1 | P21554 | 6/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017185 | 0.88 | CNR2 (0.36) | CNR2CNR1NPC1SMN1; SMN2LMNA | |
| SCHEMBL1621013 | 0.79 | HPGD (0.51) | CNR2CNR1NPC1SMN1; SMN2LMNA | |
| SCHEMBL3965097 | 0.77 | CNR2 (0.45) | CNR2CNR1SMN1; SMN2LMNAMAPT | |
| SCHEMBL1621823 | 0.73 | ITGB1 (0.43) | SMN1; SMN2LMNAITGB1ITGA4 | |
| SCHEMBL1515627 | 0.73 | ALDH1A1 (0.49) | NPC1SMN1; SMN2LMNA | |
| SCHEMBL3959595 | 0.72 | CNR1 (0.47) | CNR2CNR1SMN1; SMN2LMNAMAPT | |
| Hydrochloric Acid SCHEMBL3712256 | 0.71 | ALDH1A1 (0.48) | NPC1SMN1; SMN2LMNA | |
| SCHEMBL3964989 | 0.68 | MMP2 (0.47) | CNR2CNR1MAPT | |
| SCHEMBL15204687 | 0.66 | NPC1 (0.52) | CNR2CNR1NPC1SMN1; SMN2LMNA | |
| SCHEMBL3710378 | 0.66 | CNR2 (0.52) | CNR2CNR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | claimed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | claimed |
| EP-2074084-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | Boehringer Ingelheim International GmbH (DE) | 2009-07-01 | — | — | EP | disclosed |
| WO-2008039645-A1 | COMPOUNDS WHICH MODULATE THE CB2 RECEPTOR | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-04-03 | — | — | WO | disclosed |