SCHEMBL4017474

SCHEMBL4017474

O=C(O)OC1CC2(CCCC2)CN1

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CTSC P53634 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4024953 0.98 CTSC (0.34) CTSC
SCHEMBL11209517 0.76 CTSC (0.31) CTSC
SCHEMBL9334516 0.76 ALDH1A1 (0.34) CTSC
Hydrochloric Acid SCHEMBL10653928 0.71 BACE1 (0.39) CTSC
SCHEMBL1442126 0.71 CYP1A2 (0.50) CTSC
SCHEMBL22636233 0.71 CYP1A2 (0.50) CTSC
SCHEMBL25332799 0.69 CYP1A2 (0.48) CTSC
Hydrochloric Acid SCHEMBL27143178 0.69 CYP1A2 (0.48) CTSC
SCHEMBL4024949 0.69 CYP1A2 (0.48) CTSC
Hydrochloric Acid SCHEMBL27143177 0.69 CYP1A2 (0.48) CTSC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 57 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0854140-B1 Vitronectin receptor antagonists, their production and their use SANOFI AVENTIS DEUTSCHLAND (DE) 2013-11-06 EP disclosed
EP-0903353-B1 Imidazolidine derivates, their preparation and use, and pharmaceutical compositions containing them SANOFI AVENTIS DEUTSCHLAND (DE) 2009-11-25 EP disclosed
EP-0820988-B1 Imino derivatives as bone resorption inhibitors and vitronectin receptor antagonists HOECHST AG (DE) 2009-07-01 EP disclosed
EP-0842944-B1 Heterocycles as inhibitors of leukocyte adhesion and as antagonists of VLA-4 HOECHST AG (DE) 2003-07-09 EP disclosed
EP-0918059-B1 Substituted imidazoline derivatives, their preparation, their use, and pharmaceutical compositions containing them AVENTIS PHARMA GMBH (DE) 2003-06-25 EP disclosed
EP-0842943-B1 5-Ring heterocycles as inhibitors of leukocyte adhesion and as VLA-4 antagonists HOECHST AG (DE) 2003-02-26 EP disclosed
EP-0842945-B1 Heterocycles as inhibitors of leukocyte adhesion and as antagonists of VLA-4 HOECHST AG (DE) 2003-02-19 EP disclosed
EP-0739898-B1 Phosphonomonoester nucleic acids, methods for their preparation and their use AVENTIS PHARMA GMBH (DE) 2001-09-26 EP disclosed
EP-1077994-A1 IMIDAZOLIDINE DERIVATIVES, THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME Aventis Pharma Deutschland GmbH (DE) 2001-02-28 EP disclosed
WO-1999060015-A1 IMIDAZOLIDINE DERIVATIVES, THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME AVENTIS PHARMA DEUTSCHLAND GMBH (DE) 1999-11-25 WO disclosed
EP-0530505-A2 Hydantoin derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1993-03-10 EP disclosed
EP-0503561-A2 Method for the diastereoselective reductive pinacol coupling of homochiral alpha aminoaldehydes HOECHST AKTIENGESELLSCHAFT (DE) 1992-09-16 EP disclosed
EP-0496393-A1 Alkylation of azaglycine derivatives HOECHST AKTIENGESELLSCHAFT (DE) 1992-07-29 EP disclosed
EP-0475184-A1 Process for the production of peptides by solid phase synthesis HOECHST AKTIENGESELLSCHAFT (DE) 1992-03-18 EP disclosed
EP-0455133-A2 Peptide antagonists of bradykinin HOECHST AKTIENGESELLSCHAFT (DE) 1991-11-06 EP disclosed
EP-0449079-A2 Hydantoin derivative HOECHST AKTIENGESELLSCHAFT (DE) 1991-10-02 EP disclosed
EP-0435059-A1 Retroviral protease inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1991-07-03 EP disclosed
EP-0428849-A2 Retroviral protease inhibitors HOECHST AKTIENGESELLSCHAFT (DE) 1991-05-29 EP disclosed
EP-0413277-A1 Peptide antagonists of bradykinin HOECHST AKTIENGESELLSCHAFT (DE) 1991-02-20 EP disclosed
EP-0132580-A1 Process for the preparation of mono, bi and tricyclic aminoacids HOECHST AKTIENGESELLSCHAFT (DE) 1985-02-13 EP disclosed