Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017474 | 0.98 | CTSC (0.33) | CTSC | |
| SCHEMBL9334516 | 0.78 | ALDH1A1 (0.34) | CTSC | |
| SCHEMBL11209517 | 0.78 | CTSC (0.31) | CTSC | |
| SCHEMBL9334080 | 0.76 | ALDH1A1 (0.35) | CTSC | |
| Hydrochloric Acid SCHEMBL10653928 | 0.73 | BACE1 (0.39) | CTSC | |
| SCHEMBL25332799 | 0.72 | CYP1A2 (0.48) | CTSC | |
| SCHEMBL4024949 | 0.72 | CYP1A2 (0.48) | CTSC | |
| SCHEMBL25843766 | 0.72 | CYP1A2 (0.48) | CTSC | |
| SCHEMBL30151963 | 0.71 | CHRM3 (0.36) | — | |
| SCHEMBL22636233 | 0.69 | CYP1A2 (0.50) | CTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0854140-B1 | Vitronectin receptor antagonists, their production and their use | SANOFI AVENTIS DEUTSCHLAND (DE) | 2013-11-06 | — | — | EP | disclosed |
| EP-0903353-B1 | Imidazolidine derivates, their preparation and use, and pharmaceutical compositions containing them | SANOFI AVENTIS DEUTSCHLAND (DE) | 2009-11-25 | — | — | EP | disclosed |
| EP-0820988-B1 | Imino derivatives as bone resorption inhibitors and vitronectin receptor antagonists | HOECHST AG (DE) | 2009-07-01 | — | — | EP | disclosed |
| EP-0842944-B1 | Heterocycles as inhibitors of leukocyte adhesion and as antagonists of VLA-4 | HOECHST AG (DE) | 2003-07-09 | — | — | EP | disclosed |
| EP-0918059-B1 | Substituted imidazoline derivatives, their preparation, their use, and pharmaceutical compositions containing them | AVENTIS PHARMA GMBH (DE) | 2003-06-25 | — | — | EP | disclosed |
| EP-0842943-B1 | 5-Ring heterocycles as inhibitors of leukocyte adhesion and as VLA-4 antagonists | HOECHST AG (DE) | 2003-02-26 | — | — | EP | disclosed |
| EP-0842945-B1 | Heterocycles as inhibitors of leukocyte adhesion and as antagonists of VLA-4 | HOECHST AG (DE) | 2003-02-19 | — | — | EP | disclosed |
| EP-0739898-B1 | Phosphonomonoester nucleic acids, methods for their preparation and their use | AVENTIS PHARMA GMBH (DE) | 2001-09-26 | — | — | EP | disclosed |
| EP-1077994-A1 | IMIDAZOLIDINE DERIVATIVES, THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | Aventis Pharma Deutschland GmbH (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999060015-A1 | IMIDAZOLIDINE DERIVATIVES, THE PRODUCTION THEREOF, THEIR USE AND PHARMACEUTICAL PREPARATIONS CONTAINING THE SAME | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 1999-11-25 | — | — | WO | disclosed |
| EP-0449079-A2 | Hydantoin derivative | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-10-02 | — | — | EP | disclosed |
| EP-0435059-A1 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-07-03 | — | — | EP | disclosed |
| EP-0428849-A2 | Retroviral protease inhibitors | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-05-29 | — | — | EP | disclosed |
| EP-0413277-A1 | Peptide antagonists of bradykinin | HOECHST AKTIENGESELLSCHAFT (DE) | 1991-02-20 | — | — | EP | disclosed |
| EP-0094633-B1 | SPIRO-2-AZA-ALKANE-3-CARBONITRILES, PROCESS FOR THEIR PREPARATION AND THEIR USE | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-11-09 | — | — | EP | disclosed |
| EP-0115345-B1 | PROCESS FOR THE RESOLUTION OF RACEMIC OPTICALLY ACTIVE BICYCLIC IMINO-ALPHA-CARBOXYLIC ACID ESTERS AND USE OF THE COMPOUNDS OBTAINABLE IN THIS WAY FOR THE SYNTHESIS OF CARBOXYALKYL DIPEPTIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-01-07 | — | — | EP | disclosed |
| EP-0132580-A1 | Process for the preparation of mono, bi and tricyclic aminoacids | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-02-13 | — | — | EP | disclosed |
| EP-0115345-A1 | Process for the resolution of racemic optically active bicyclic imino-alpha-carboxylic acid esters and use of the compounds obtainable in this way for the synthesis of carboxyalkyl dipeptides | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-08-08 | — | — | EP | disclosed |
| EP-0094633-A2 | Spiro-2-aza-alkane-3-carbonitriles, process for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-11-23 | — | — | EP | disclosed |
| EP-0090341-A2 | Spiro-(4,(3+n))-2-aza-alkan-3-carboxylic-acid derivatives, process for their preparation,agents containing them and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-10-05 | — | — | EP | disclosed |