Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CTSC | P53634 | 2/20 | 0.33 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9334080 | 0.98 | ALDH1A1 (0.35) | ALDH1A1CTSCSOAT1 | |
| SCHEMBL4024953 | 0.78 | CTSC (0.34) | CTSC | |
| SCHEMBL4017474 | 0.76 | CTSC (0.33) | CTSC | |
| SCHEMBL9337728 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CTSCKDM4E | |
| SCHEMBL10468840 | 0.76 | ALDH1A1 (0.40) | ALDH1A1CTSCKDM4E | |
| SCHEMBL10468498 | 0.74 | ALDH1A1 (0.38) | ALDH1A1CTSCKDM4E | |
| SCHEMBL9337548 | 0.72 | ALDH1A1 (0.35) | ALDH1A1SOAT1KDM4E | |
| SCHEMBL25232302 | 0.71 | CYP2D6 (0.36) | ALDH1A1CTSCKDM4E | |
| SCHEMBL9337736 | 0.70 | ALDH1A1 (0.32) | ALDH1A1SOAT1 | |
| SCHEMBL9334513 | 0.70 | ALDH1A1 (0.36) | ALDH1A1SOAT1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268975-B1 | Process for the preparation of mono, bi and tricyclic amino acids, intermediary compounds and their preparation | HOECHST AG (DE) | 1994-05-25 | — | — | EP | disclosed |
| EP-0268975-A2 | Process for the preparation of mono, bi and tricyclic amino acids, intermediary compounds and their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1988-06-01 | — | — | EP | disclosed |