Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAOB | P27338 | 8/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4755471 | 1.00 | MEN1 (0.46) | MEN1KMT2AMAOBMAOANFKB1 | |
| SCHEMBL4017359 | 0.89 | MEN1 (0.49) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL4017528 | 0.89 | MEN1 (0.49) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL13982583 | 0.87 | MEN1 (0.48) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL4017822 | 0.87 | GAA (0.55) | MEN1KMT2AMAOBGAALMNA | |
| SCHEMBL13982460 | 0.87 | MEN1 (0.47) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL4017825 | 0.85 | MMP1 (0.50) | MEN1KMT2ABACE1LMNASMN1; SMN2 | |
| SCHEMBL4669261 | 0.85 | ALDH1A1 (0.48) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL4017363 | 0.85 | MEN1 (0.62) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL4667926 | 0.84 | MEN1 (0.45) | MEN1KMT2AGAALMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | claimed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | claimed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008152097-A1 | CINNAMIC ACID DERIVATIVES AS MODULATORS OF THE EP2 RECEPTOR | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-12-18 | — | — | WO | disclosed |
| EP-2003118-A1 | Cinnamic acid derivatives as modulators of EP2 receptors | Bayer Schering Pharma Aktiengesellschaft (DE) | 2008-12-17 | — | — | EP | disclosed |