SCHEMBL401764

SCHEMBL401764

CCC(=O)NCCNC(=O)CC(=O)OCCOc1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.47

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
RECQL P46063 1/20 0.47
POLB P06746 1/20 0.43
ACACB O00763 1/20 0.42
MAPT P10636 4/20 0.42
SMN1; SMN2 Q16637 1/20 0.41
HTT P42858 3/20 0.40
AGTR1 P30556 1/20 0.40
CYP2C19 P33261 1/20 0.40
OPRK1 P41145 1/20 0.40
UBE2N P61088 1/20 0.40
LMNA P02545 1/20 0.40
HSP90AA1 P07900 1/20 0.40
KMT2A Q03164 1/20 0.40
MTNR1A P48039 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838367 0.95 MAPT (0.44) POLBMAPTSMN1; SMN2LMNAKMT2A
SCHEMBL14369609 0.93 SMN1; SMN2 (0.46) POLBMAPTSMN1; SMN2HTTAGTR1
SCHEMBL838083 0.93 MAPT (0.49) POLBMAPTSMN1; SMN2
SCHEMBL10029314 0.92 MAPT (0.44) POLBMAPTSMN1; SMN2KMT2AMTNR1A
SCHEMBL402847 0.92 MAPT (0.41) POLBMAPTSMN1; SMN2KMT2A
SCHEMBL838506 0.92 MAPT (0.45) RECQLPOLBMAPTSMN1; SMN2KMT2A
SCHEMBL4758832 0.91 USP2 (0.41) POLBMAPTSMN1; SMN2KMT2AMTNR1A
SCHEMBL10030725 0.91 USP2 (0.41) RECQLPOLBMAPTSMN1; SMN2HTT
SCHEMBL12091364 0.91 MAPT (0.43) POLBMAPTSMN1; SMN2CYP2C19KMT2A
SCHEMBL4747310 0.91 MAPT (0.40) POLBMAPTSMN1; SMN2HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8449095-B2 Radiation curable solid ink compositions suitable for transfuse printing applications XEROX CORPORATION (US) 2013-05-28 US disclosed
US-20120287199-A1 High Reactivity Curable Paste Ink Compositions XEROX CORPORATION (US) 2012-11-15 US disclosed
US-8308286-B2 Curable phase change ink containing alkoxysilane monomer XEROX CORPORATION (US) 2012-11-13 US disclosed
US-20120062669-A1 CURABLE PHASE CHANGE INK CONTAINING ALKOXYSILANE MONOMER XEROX CORPORATION (US) 2012-03-15 US disclosed
US-8124193-B2 Gloss control of UV curable formulations through micro-patterning XEROX CORPORATION (US) 2012-02-28 US disclosed
US-8105659-B2 Method of controlling gloss with curing atmosphere using radiation curable ink or overcoat compositions XEROX CORPORATION (US) 2012-01-31 US disclosed
US-20120013690-A1 RADIATION CURABLE SOLID INK COMPOSITIONS SUITABLE FOR TRANSFUSE PRINTING APPLICATIONS XEROX CORPORATION (US) 2012-01-19 US disclosed
US-20100227075-A1 GLOSS CONTROL OF UV CURABLE FORMULATIONS THROUGH MICRO-PATTERNING XEROX CORPORATION (US) 2010-09-09 US disclosed
US-20100116424-A1 ORGANIC PHASE CHANGE CARRIERS CONTAINING NANOPARTICLES, PHASE CHANGE INKS INCLUDING SAME AND METHODS FOR MAKING SAME XEROX CORPORATION (US) 2010-05-13 US disclosed
US-20100055423-A1 Machine Readable Code Comprising Ultra-Violet Curable Gellant Inks XEROX CORPORATION (US) 2010-03-04 US disclosed
US-20100053287-A1 Ultra-Violet Curable Gellant Inks For Braille, Raised Print, And Regular Print Applications XEROX CORPORATION (US) 2010-03-04 US disclosed
US-20100021698-A1 METHOD OF CONTROLLING GLOSS WITH CURING ATMOSPHERE USING RADIATION CURABLE INK OR OVERCOAT COMPOSITIONS XEROX CORPORATION (US) 2010-01-28 US disclosed
US-7625956-B2 Phase change inks containing photoinitiator with phase change properties and gellant affinity XEROX CORPORATION (US) 2009-12-01 US disclosed
US-20070120910-A1 Phase change inks containing photoinitiator with phase change properties and gellant affinity XEROX CORPORATION 2007-05-31 US disclosed