SCHEMBL838083

SCHEMBL838083

CCOC(=O)CC(=O)NCCNC(=O)CC(=O)OCCOc1ccc(C(=O)C(C)(C)O)cc1

nearest known ligand 0.49

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.49
SMN1; SMN2 Q16637 2/20 0.48
POLB P06746 1/20 0.45
NPC1 O15118 2/20 0.44
RAB9A P51151 1/20 0.44
TSHR P16473 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838367 0.95 MAPT (0.44) MAPTSMN1; SMN2POLBNPC1RAB9A
SCHEMBL14369609 0.93 SMN1; SMN2 (0.46) MAPTSMN1; SMN2POLBNPC1RAB9A
SCHEMBL401764 0.93 RECQL (0.47) MAPTSMN1; SMN2POLB
SCHEMBL12036667 0.92 MAPT (0.53) MAPTSMN1; SMN2POLBRAB9A
SCHEMBL402847 0.92 MAPT (0.41) MAPTSMN1; SMN2POLBNPC1RAB9A
SCHEMBL838506 0.92 MAPT (0.45) MAPTSMN1; SMN2POLBNPC1RAB9A
SCHEMBL10029314 0.92 MAPT (0.44) MAPTSMN1; SMN2POLBNPC1RAB9A
SCHEMBL10030725 0.91 USP2 (0.41) MAPTSMN1; SMN2POLBNPC1RAB9A
SCHEMBL12091364 0.91 MAPT (0.43) MAPTSMN1; SMN2POLBNPC1RAB9A
SCHEMBL4758832 0.91 USP2 (0.41) MAPTSMN1; SMN2POLBNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150145920-A1 METHOD OF JETTING INK XEROX CORPORATION (US) 2015-05-28 US disclosed
US-9022546-B1 Method of jetting ink XEROX CORPORATION (US) 2015-05-05 US disclosed
US-9005484-B2 Low polarity nano silver gels XEROX CORPORATION (US) 2015-04-14 US disclosed
US-8916084-B2 Ultra-violet curable gellant inks for three-dimensional printing and digital fabrication applications XEROX CORPORATION (US) 2014-12-23 US disclosed
US-8791202-B2 Phase change ink compositions XEROX CORPORATION (US) 2014-07-29 US disclosed
US-8758865-B2 Ultra-violet curable gellant inks for tactile and regular print applications for signature and document authentication XEROX CORPORATION (US) 2014-06-24 US disclosed
US-20120236065-A1 Magnetic Curable Inks XEROX CORPORATION (US) 2012-09-20 US disclosed
US-20120123014-A1 OVERPRINT VARNISH FORMULATIONS XEROX CORPORATION (US) 2012-05-17 US disclosed
US-8177897-B2 Phase change inks containing graphene-based carbon allotrope colorants XEROX CORPORATION (US) 2012-05-15 US disclosed
US-8142557-B2 Radiation curable ink containing gellant and radiation curable wax XEROX CORPORATION (US) 2012-03-27 US disclosed
US-20100055415-A1 Ultra-Violet Curable Gellant Inks For Tactile And Regular Print Applications For Signature And Document Authentication XEROX CORPORATION (US) 2010-03-04 US disclosed
US-7625956-B2 Phase change inks containing photoinitiator with phase change properties and gellant affinity XEROX CORPORATION (US) 2009-12-01 US disclosed
US-20090258155-A1 CURABLE OVERCOAT COMPOSITIONS XEROX CORPORATION (US) 2009-10-15 US disclosed
US-20090082489-A1 Phase change ink compositions XEROX CORPORATION 2009-03-26 US disclosed
US-20090046134-A1 Phase change ink compositions XEROX CORPORATION 2009-02-19 US disclosed
US-20080000384-A1 RADIATION CURABLE INK CONTAINING GELLANT AND RADIATION CURABLE WAX XEROX CORPORATION (US) 2008-01-03 US disclosed
US-20070283846-A1 Organic Phase Change Carriers Containing Nanoparticles, Phase Change Inks Including Same and Methods for Making Same XEROX CORPORATION (US) 2007-12-13 US disclosed
US-7279587-B2 Photoinitiator with phase change properties and gellant affinity XEROX CORPORATION (US) 2007-10-09 US disclosed
US-20070123723-A1 Photoinitiator with phase change properties and gellant affinity XEROX CORPORATION 2007-05-31 US disclosed
US-20070120910-A1 Phase change inks containing photoinitiator with phase change properties and gellant affinity XEROX CORPORATION 2007-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070123723-A1 Photoinitiator with phase change properties and gellant affinity NR2E3, NR4A1, NR4A3 MAPT 2052/4885SMN1; SMN2 4426/4885POLB 1052/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.