SCHEMBL838367

SCHEMBL838367

CC(C)(O)C(=O)c1ccc(OCCOC(=O)CC(=O)NCCNC(=O)CC(=O)OCCOc2ccc(C(=O)C(C)(C)O)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
POLB P06746 2/20 0.43
NPC1 O15118 2/20 0.42
USP2 O75604 1/20 0.42
ALOX15 P16050 1/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
RAB9A P51151 3/20 0.40
CASP3 P42574 1/20 0.40
SENP7 Q9BQF6 1/20 0.40
ALDH1A1 P00352 1/20 0.40
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL402847 0.96 MAPT (0.41) MAPTPOLBNPC1USP2ALOX15
SCHEMBL10029314 0.96 MAPT (0.44) MAPTPOLBNPC1USP2ALOX15
SCHEMBL4758832 0.95 USP2 (0.41) MAPTPOLBNPC1USP2ALOX15
SCHEMBL14369609 0.95 SMN1; SMN2 (0.46) MAPTPOLBNPC1MAPK1SMN1; SMN2
SCHEMBL401764 0.95 RECQL (0.47) MAPTPOLBSMN1; SMN2KMT2ALMNA
SCHEMBL12091364 0.95 MAPT (0.43) MAPTPOLBNPC1SMN1; SMN2MEN1
SCHEMBL838083 0.95 MAPT (0.49) MAPTPOLBNPC1TSHRSMN1; SMN2
SCHEMBL10030725 0.95 USP2 (0.41) MAPTPOLBNPC1USP2ALOX15
SCHEMBL1707907 0.95 USP2 (0.50) MAPTPOLBNPC1USP2ALOX15
SCHEMBL4747310 0.95 MAPT (0.40) MAPTPOLBNPC1USP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150145920-A1 METHOD OF JETTING INK XEROX CORPORATION (US) 2015-05-28 US disclosed
US-9022546-B1 Method of jetting ink XEROX CORPORATION (US) 2015-05-05 US disclosed
US-9005484-B2 Low polarity nano silver gels XEROX CORPORATION (US) 2015-04-14 US disclosed
US-8916084-B2 Ultra-violet curable gellant inks for three-dimensional printing and digital fabrication applications XEROX CORPORATION (US) 2014-12-23 US disclosed
US-8791202-B2 Phase change ink compositions XEROX CORPORATION (US) 2014-07-29 US disclosed
US-8758865-B2 Ultra-violet curable gellant inks for tactile and regular print applications for signature and document authentication XEROX CORPORATION (US) 2014-06-24 US disclosed
US-8361562-B2 Ink compositions XEROX CORPORATION (US) 2013-01-29 US disclosed
US-20120236065-A1 Magnetic Curable Inks XEROX CORPORATION (US) 2012-09-20 US disclosed
US-8177897-B2 Phase change inks containing graphene-based carbon allotrope colorants XEROX CORPORATION (US) 2012-05-15 US disclosed
US-8142557-B2 Radiation curable ink containing gellant and radiation curable wax XEROX CORPORATION (US) 2012-03-27 US disclosed
US-7625956-B2 Phase change inks containing photoinitiator with phase change properties and gellant affinity XEROX CORPORATION (US) 2009-12-01 US disclosed
US-20090258155-A1 CURABLE OVERCOAT COMPOSITIONS XEROX CORPORATION (US) 2009-10-15 US disclosed
US-7556844-B2 Radiation curable photochromic inks XEROX CORPORATION (US) 2009-07-07 US disclosed
US-20090082489-A1 Phase change ink compositions XEROX CORPORATION 2009-03-26 US disclosed
US-20080000384-A1 RADIATION CURABLE INK CONTAINING GELLANT AND RADIATION CURABLE WAX XEROX CORPORATION (US) 2008-01-03 US disclosed
US-20070283846-A1 Organic Phase Change Carriers Containing Nanoparticles, Phase Change Inks Including Same and Methods for Making Same XEROX CORPORATION (US) 2007-12-13 US disclosed
US-7279587-B2 Photoinitiator with phase change properties and gellant affinity XEROX CORPORATION (US) 2007-10-09 US disclosed
US-20070211110-A1 RADIATION CURABLE PHOTOCHROMIC INKS XEROX CORPORATION (US) 2007-09-13 US disclosed
US-20070123723-A1 Photoinitiator with phase change properties and gellant affinity XEROX CORPORATION 2007-05-31 US disclosed
US-20070120910-A1 Phase change inks containing photoinitiator with phase change properties and gellant affinity XEROX CORPORATION 2007-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070123723-A1 Photoinitiator with phase change properties and gellant affinity NR2E3, NR4A1, NR4A3 MAPT 2052/4885POLB 1052/4885NPC1 2461/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.