SCHEMBL402847

SCHEMBL402847

CC(C)(C)C(=O)c1ccc(OCCOC(=O)CC(=O)NCCNC(=O)CC(=O)OCCOc2ccc(C(=O)C(C)(C)O)cc2)cc1

nearest known ligand 0.41

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.41
POLB P06746 2/20 0.41
SMN1; SMN2 Q16637 1/20 0.39
NPC1 O15118 2/20 0.39
USP2 O75604 1/20 0.39
ALOX15 P16050 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
HSD17B10 Q99714 1/20 0.39
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
RAB9A P51151 3/20 0.38
CASP3 P42574 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
ALDH1A1 P00352 1/20 0.38
KDM4E B2RXH2 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL838367 0.96 MAPT (0.44) MAPTPOLBSMN1; SMN2NPC1USP2
SCHEMBL12233785 0.93 POLB (0.37) MAPTPOLBSMN1; SMN2NPC1USP2
SCHEMBL15489690 0.93 MAPT (0.39) MAPTPOLBSMN1; SMN2NPC1USP2
SCHEMBL10029314 0.93 MAPT (0.44) MAPTPOLBSMN1; SMN2NPC1USP2
SCHEMBL838083 0.92 MAPT (0.49) MAPTPOLBSMN1; SMN2NPC1TSHR
SCHEMBL10030725 0.92 USP2 (0.41) MAPTPOLBSMN1; SMN2NPC1USP2
SCHEMBL4758832 0.92 USP2 (0.41) MAPTPOLBSMN1; SMN2NPC1USP2
SCHEMBL12091364 0.92 MAPT (0.43) MAPTPOLBSMN1; SMN2NPC1MEN1
SCHEMBL14369609 0.92 SMN1; SMN2 (0.46) MAPTPOLBSMN1; SMN2NPC1MAPK1
SCHEMBL401764 0.92 RECQL (0.47) MAPTPOLBSMN1; SMN2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170210922-A1 3D PRINTING SYSTEM COMPRISING SOLID BUILD INK COMPRISING COLORANT XEROX CORPORATION 2017-07-27 US disclosed
US-9676952-B2 3D printing system comprising solid build ink comprising colorant XEROX CORPORATION (US) 2017-06-13 US disclosed
US-20160244628-A1 3D PRINTING SYSTEM COMPRISING SOLID BUILD INK COMPRISING COLORANT XEROX CORPORATION 2016-08-25 US disclosed
US-20150145920-A1 METHOD OF JETTING INK XEROX CORPORATION (US) 2015-05-28 US disclosed
US-9022546-B1 Method of jetting ink XEROX CORPORATION (US) 2015-05-05 US disclosed
US-20140171537-A1 Orange Curable Ink XEROX CORPORATION (US) 2014-06-19 US disclosed
US-8714723-B2 Robust curable solid inks and methods for using the same XEROX CORPORATION (US) 2014-05-06 US disclosed
US-8669298-B1 Green curable ink XEROX CORPORATION (US) 2014-03-11 US disclosed
US-8652720-B2 Super low melt toners XEROX CORPORATION (US) 2014-02-18 US disclosed
US-8652574-B2 Ink compositions XEROX CORPORATION (US) 2014-02-18 US disclosed
US-20120282448-A1 METHODS FOR FABRICATING THREE-DIMENSIONAL OBJECTS XEROX CORPORATION (US) 2012-11-08 US disclosed
US-8262210-B2 Curable gel inks with reduced syneresis and halo formation XEROX CORPORATION (US) 2012-09-11 US disclosed
US-20120224230-A1 WATERMARKING COMPRISING ULTRAVIOLET CURABLE SOLID INKS AND METHODS FOR PRODUCING THE SAME XEROX CORPORATION (US) 2012-09-06 US disclosed
US-20120092426-A1 CURABLE PHASE CHANGE INKS CONTAINING FUNCTIONALIZED ISOSORBIDES XEROX CORPORATION (US) 2012-04-19 US disclosed
US-8142557-B2 Radiation curable ink containing gellant and radiation curable wax XEROX CORPORATION (US) 2012-03-27 US disclosed
US-20120062669-A1 CURABLE PHASE CHANGE INK CONTAINING ALKOXYSILANE MONOMER XEROX CORPORATION (US) 2012-03-15 US disclosed
US-8124193-B2 Gloss control of UV curable formulations through micro-patterning XEROX CORPORATION (US) 2012-02-28 US disclosed
US-8105659-B2 Method of controlling gloss with curing atmosphere using radiation curable ink or overcoat compositions XEROX CORPORATION (US) 2012-01-31 US disclosed
US-8043665-B2 Method of controlling gloss in UV curable overcoat compostitions XEROX CORPORATION (US) 2011-10-25 US disclosed
US-20110177246-A1 INK COMPOSITIONS XEROX CORPORATION (US) 2011-07-21 US disclosed