SCHEMBL4017923

SCHEMBL4017923

COC(=O)C1CC/C=C\CCC1

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.47
TP53 P04637 1/20 0.42
POLB P06746 1/20 0.40
HTT P42858 1/20 0.38
KMT2A Q03164 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 2/20 0.37
CHRNB2 P17787 2/20 0.37
CHRNA4 P43681 2/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CHRNA7 P36544 1/20 0.37
GAA P10253 1/20 0.37
KDM4E B2RXH2 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4017926 1.00 SMN1; SMN2 (0.47) SMN1; SMN2TP53POLBHTTKMT2A
SCHEMBL25161948 1.00 SMN1; SMN2 (0.47) SMN1; SMN2TP53POLBHTTKMT2A
SCHEMBL5046323 0.92 TP53 (0.47) SMN1; SMN2TP53POLBALDH1A1CHRNB2
Cyclohexene SCHEMBL704338 0.85 TDP1 (0.43) SMN1; SMN2TP53POLBHTTKMT2A
SCHEMBL10126493 0.83 HTT (0.41) SMN1; SMN2POLBHTTKMT2ATDP1
SCHEMBL91215 0.82 TDP1 (0.46) SMN1; SMN2TP53HTTKMT2ATDP1
SCHEMBL11982130 0.82 TDP1 (0.46) SMN1; SMN2TP53HTTKMT2ATDP1
SCHEMBL9613490 0.82 TDP1 (0.46) SMN1; SMN2TP53HTTKMT2ATDP1
SCHEMBL4015654 0.81 SMN1; SMN2 (0.45) SMN1; SMN2TP53POLBHTTKMT2A
SCHEMBL4015650 0.81 SMN1; SMN2 (0.45) SMN1; SMN2TP53POLBHTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7504465-B2 Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2009-03-17 US claimed
US-20080312393-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof BAUGH LISA S 2008-12-18 US claimed
EP-1704172-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF ExxonMobil Research and Engineering Company (US) 2006-09-27 EP claimed
WO-2005063834-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-07-14 WO claimed
US-20050137369-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2005-06-23 US claimed
EP-4382129-A2 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE Tagworks Pharmaceuticals B.V. (NL) 2024-06-12 EP disclosed
EP-3983363-B1 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE TAGWORKS PHARMACEUTICALS B V (NL) 2024-04-10 EP disclosed
US-20230121556-A1 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE TAGWORKS PHARMACEUTICALS B.V. (NL) 2023-04-20 US disclosed
CN-115135628-A Compounds for fast and efficient click release 泰克沃尔科斯制药有限公司 2022-09-30 CN disclosed
EP-3983363-A1 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE Tagworks Pharmaceuticals B.V. (NL) 2022-04-20 EP disclosed
WO-2020256546-A1 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE TAGWORKS PHARMACEUTICALS B.V. (NL) 2020-12-24 WO disclosed
EP-2781531-B1 POLYMER AND SOLAR ENCAPSULANT USING SAME SUMITOMO CHEMICAL CO (JP) 2017-07-12 EP disclosed
US-20080312393-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and methods of making thereof BAUGH LISA S 2008-12-18 US disclosed
US-7402642-B2 Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-07-22 US disclosed
US-7402642-B2 Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-07-22 US disclosed
US-7402642-B2 Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2008-07-22 US disclosed
EP-1704172-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF ExxonMobil Research and Engineering Company (US) 2006-09-27 EP disclosed
WO-2005063834-A1 LINEAR FUNCTIONAL COPOLYMERS OF ETHYLENE WITH PRECISE AND MINIMUM RUN LENGTH DISTRIBUTIONS AND METHODS OF MAKING THEREOF EXXONMOBIL RESEARCH AND ENGINEERING COMPANY (US) 2005-07-14 WO disclosed
US-20050137369-A1 Linear functional copolymers of ethylene with precise and minimum run length distributions and method of making thereof EXXONMOBIL RESEARCH AND ENGINEERING COMPANY 2005-06-23 US disclosed
EP-0409273-A2 Substituted isoxazole and isothiazole derivatives F. HOFFMANN-LA ROCHE AG (CH) 1991-01-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230121556-A1 COMPOUNDS FOR FAST AND EFFICIENT CLICK RELEASE LTB4R, LTC4S, LTA4H SMN1; SMN2 3664/4885TP53 4373/4885POLB 3205/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.