Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.51 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ATP4A | P20648 | 10/20 | 0.49 |
| ▸ | ATP4B | P51164 | 10/20 | 0.49 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.49 |
| ▸ | TUBB | P07437 | 2/20 | 0.49 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.49 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017957 | 1.00 | RAB9A (0.54) | RAB9AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL28280854 | 0.86 | MEN1 (0.50) | RAB9AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL825345 | 0.83 | MEN1 (0.66) | RAB9AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL825346 | 0.83 | MEN1 (0.66) | RAB9AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL4012221 | 0.82 | RAB9A (0.49) | RAB9AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL28156830 | 0.82 | RAB9A (0.47) | RAB9AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL4360035 | 0.82 | MAPT (0.59) | RAB9AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL4360036 | 0.82 | MAPT (0.59) | RAB9AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL28156829 | 0.81 | RAB9A (0.45) | RAB9AMEN1MAPTKMT2AKDM4E | |
| SCHEMBL13936229 | 0.80 | ATP4A (0.66) | RAB9AMEN1MAPTKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009085226-A2 | INHIBITORS OF CDC2-LIKE KINASES (CLKS) AND METHODS OF USE THEREOF | SIRTRIS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009085226-A2 | INHIBITORS OF CDC2-LIKE KINASES (CLKS) AND METHODS OF USE THEREOF | SIRTRIS PHARMACEUTICALS, INC. (US) | 2009-07-09 | — | — | WO | disclosed |